High-strength apatitic cement by modification with superplasticizers

被引:28
|
作者
Fernández, E
Sarda, S
Hamcerencu, M
Vlad, MD
Gel, M
Valls, S
Torres, R
López, J
机构
[1] Tech Univ Catalonia, IRGASC, Div Bioengn & Biomat, UPC, E-08028 Barcelona, Spain
[2] Univ Toulouse 3, LCBM, IUT A, F-81100 Castres, France
[3] UPC, Dept Bldg Engn, E-08034 Barcelona, Spain
关键词
calcium phosphate cement; bone tissue engineering; mechanical properties; osteoporosis; superplasticizer;
D O I
10.1016/j.biomaterials.2004.07.043
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
This study reports on a novel method to improve the strength of apatitic bone cements. The liquid phase of Biocement-H-(C) was modified with commercial superplasticizers. The results showed that small additions, i.e. 0.5 vol%, in the aqueous liquid phase improved the maximum compressive strength of Biocement-H-(C) (35 MPa) by 71 %, i.e. 60 MPa. Moreover, the addition of high amounts of superplasticizers, i.e. 50 vol.%, allowed for a significant reduction of the liquid-to-powder ratio from 0.32 to 0.256 mL/g, without affecting the maximum strength and/or the workability of the cement. These results open up new ways to develop injectable and high-strength apatitic bone cements for load-bearing applications. (C) 2004 Elsevier Ltd. All rights reserved.
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页码:2289 / 2296
页数:8
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