Pulmonary alveolar proteinosis (PAP) in idiopathic hypoparathyroidism

被引:1
|
作者
Saha, Soma [1 ]
Madan, Karan [2 ]
Jain, Deepali [3 ]
Goswami, Ravinder [1 ]
机构
[1] All India Inst Med Sci, Endocrinol & Metab, Delhi, India
[2] All India Inst Med Sci, Pulm Med & Sleep Disorders, Delhi, India
[3] All India Inst Med Sci, Pathol, Delhi, India
关键词
endocrine system; respiratory medicine;
D O I
10.1136/bcr-2019-231053
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Idiopathic hypoparathyroidism (IH) and autoimmune pulmonary alveolar proteinosis (PAP) are rare disorders. A patient with IH and optimal calcaemic control on calcium and alfacalcidol was detected to have PAP after 8 years of follow-up. Patient had no respiratory complaints. Routine abdominal imaging for renal calcification showed patchy ground glass opacities in the lower lung fields leading to incidental diagnosis of PAP. Pulmonary function tests showed impaired diffusion capacity of the lung. Anti-granulocyte macrophage-colony stimulating factor autoantibodies were positive. Patient regularly attended the pulmonary clinic and showed progressive improvement in diffusion capacity of the lung during 2 years of follow-up. The calcaemic control in IH remained stable despite its presence with PAP. The autoimmune PAP in the presented case suggests a possible autoimmune basis of IH.
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页数:3
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