Pulmonary alveolar proteinosis (PAP) in idiopathic hypoparathyroidism

被引:1
|
作者
Saha, Soma [1 ]
Madan, Karan [2 ]
Jain, Deepali [3 ]
Goswami, Ravinder [1 ]
机构
[1] All India Inst Med Sci, Endocrinol & Metab, Delhi, India
[2] All India Inst Med Sci, Pulm Med & Sleep Disorders, Delhi, India
[3] All India Inst Med Sci, Pathol, Delhi, India
关键词
endocrine system; respiratory medicine;
D O I
10.1136/bcr-2019-231053
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Idiopathic hypoparathyroidism (IH) and autoimmune pulmonary alveolar proteinosis (PAP) are rare disorders. A patient with IH and optimal calcaemic control on calcium and alfacalcidol was detected to have PAP after 8 years of follow-up. Patient had no respiratory complaints. Routine abdominal imaging for renal calcification showed patchy ground glass opacities in the lower lung fields leading to incidental diagnosis of PAP. Pulmonary function tests showed impaired diffusion capacity of the lung. Anti-granulocyte macrophage-colony stimulating factor autoantibodies were positive. Patient regularly attended the pulmonary clinic and showed progressive improvement in diffusion capacity of the lung during 2 years of follow-up. The calcaemic control in IH remained stable despite its presence with PAP. The autoimmune PAP in the presented case suggests a possible autoimmune basis of IH.
引用
收藏
页数:3
相关论文
共 50 条
  • [1] Pulmonary Alveolar Proteinosis (PAP)
    Patel, S.
    Gandhi, D.
    Patel, D.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2019, 199
  • [2] Pulmonary Alveolar Proteinosis (PAP)
    Riley, Leonard
    Wang, Tisha
    Ataya, Ali
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2019, 200 (08)
  • [3] PATHOGENESIS OF PULMONARY ALVEOLAR PROTEINOSIS (PAP)
    PARK, BH
    BIGGAR, WD
    COOPER, JD
    HEINER, DC
    WASSERMAN, K
    FEDERATION PROCEEDINGS, 1978, 37 (06) : 1454 - 1454
  • [4] STUDIES ON PULMONARY ALVEOLAR PROTEINOSIS (PAP)
    PARK, BH
    WASSERMAN, K
    AJUGWO, R
    HEINER, DC
    PEDIATRIC RESEARCH, 1975, 9 (04) : 399 - 399
  • [5] PULMONARY ALVEOLAR PROTEINOSIS (PAP) - AN UPDATE
    KARIMAN, K
    SPOCK, A
    KYLSTRA, JA
    AMERICAN REVIEW OF RESPIRATORY DISEASE, 1983, 127 (04): : 91 - 91
  • [6] PULMONARY WASHINGS AND BLOOD IN PULMONARY ALVEOLAR PROTEINOSIS (PAP)
    SIEGER, L
    STRATTON, JA
    WASSERMAN, K
    PEDIATRIC RESEARCH, 1977, 11 (04) : 579 - 579
  • [7] Serologic Diagnosis of Pulmonary Alveolar Proteinosis (PAP).
    Uchida, K.
    Nakata, K.
    Koch, D. E.
    Carey, B. C.
    Suzuki, T.
    Stevens, C. A.
    Yamada, Y.
    Trapnell, B. C.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2009, 179
  • [8] The healthcare burden of pulmonary alveolar proteinosis (PAP)
    Lee, Elinor
    Ataya, Ali
    Mccarthy, Cormac
    Godart, Erica
    Cosenza, John
    King, Alysse
    Robinson, Brian
    Wang, Tisha
    ORPHANET JOURNAL OF RARE DISEASES, 2025, 20 (01)
  • [9] PULMONARY ALVEOLAR PROTEINOSIS (PAP) IN SCID MICE
    JENNINGS, VM
    DILLEHAY, DL
    WEBB, SK
    BROWN, LAS
    FASEB JOURNAL, 1995, 9 (04): : A968 - A968
  • [10] Pulmonary Alveolar Proteinosis (PAP) After Lung Transplant
    Thachuthara-George, Joseph
    Neeraj, Sinha
    Buckner, Brian
    Mankidy, Babith
    Scheinin, Scott
    Kaleekal, Thomas
    CHEST, 2015, 148 (04)