TUMOR CELL GROWTH SUBJECTED TO CORRELATED NOISES AND TIME DELAY

被引：0
|
作者：
Feng, Y. L. [1 ]
Gao, L. L. [1 ]
Liu, Y. F. [1 ]
Zhang, M. [1 ]
Dong, J. M. [2 ]
机构：
[1] Lanzhou Univ, Hosp 2, Lanzhou 730000, Peoples R China
[2] Chinese Acad Sci, Inst Modern Phys, Lanzhou 730000, Peoples R China
来源：
JOURNAL OF MECHANICS IN MEDICINE AND BIOLOGY | 2016年 / 16卷 / 02期
基金：
中国国家自然科学基金;
关键词：
Tumor cell growth; correlated noise; time delay; COMPUTER-SIMULATION; ANTITUMOR MODEL; FEMALE BREAST; COLOR NOISES; SYSTEM; EXTINCTION; DRIVEN; CANCER;
D O I：
10.1142/S0219519416500159
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
The tumor cell growth with time -delayed feedback driven by correlated noises under the immune surveillance are investigated within an anti -tumor model. The effects of the noise correlation strength and time delay on the stationary probability distribution, the average tumor cell population and the mean first passage time (MFPT) are analyzed in detail based on the delay Fokker Planck equation. The effects of the correlation strength and time delay could play the same role in the average tumor cell population, but play opposite role in the MFPT. In addition, the role of the correlation strength and time delay for different activation thresholds of immune system is explored.
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页数：10
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