A New Diphenylethylene from Arundina graminifolia and Its Cytotoxicity

被引：8
|
作者：
Gao, Yan [1 ]
Jin, Yongcan [2 ]
Yang, Shuai [2 ]
Wu, Jiao [2 ]
Gao, Xuemei [3 ]
Hu, Qiufen [3 ,4 ]
Ma, Yinhai [1 ]
机构：
[1] Kunming Univ, Chem Sci & Technol Dept, Kunming 650214, Peoples R China
[2] Yunnan Acad Tobacco Sci, Key Lab Tobacco Chem Yunnan Prov, Kunming 650106, Peoples R China
[3] Yunnan Univ Nationalities, State Ethn Affairs Commiss, Key Lab Chem Ethn Med Resources, Kunming 650031, Peoples R China
[4] Yunnan Univ Nationalities, Minist Educ, Kunming 650031, Peoples R China
来源：
ASIAN JOURNAL OF CHEMISTRY | 2014年 / 26卷 / 13期
基金：
中国国家自然科学基金;
关键词：
Arundina graminifolia; Diphenylethylene; Structure elucidation; Cytotoxicity; PHENOLIC-COMPOUNDS;
D O I：
10.14233/ajchem.2014.16010
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A new diphenylethylenes, gramniphenol J (1), was isolated from Arundina graminifolia. Its structure was elucidated by spectroscopic methods including extensive 1D- and 2D-NMR techniques. Compound 1 was evaluated for its cytotoxicity against five human tumor cell lines and showed cytotoxicity against PC3 and SHSY5Y cells with IC50 values of 8.2 and 7.6 mu M.
引用
收藏
页码：3903 / 3905
页数：3
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