Nutritional Value and Biological Activities of Sea Cucumber Holothuria scabra Cultured in the Open Pond System

被引:7
|
作者
Wulandari, Diah Anggraini [1 ]
Gustini, Nunik [1 ]
Murniasih, Tutik [1 ]
Bayu, Asep [1 ]
Sari, Martha [1 ]
Syahputra, Gita [1 ]
Harahap, Iskandar Azmy [1 ]
Rasyid, Abdullah [1 ]
Moria, Sari Budi [2 ]
Rahmawati, Siti Irma [1 ]
Izzati, Fauzia Nurul [1 ]
Septiana, Eris [1 ]
Rachman, Fauzy [1 ]
Putra, Masteria Yunovilsa [1 ]
机构
[1] Natl Res & Innovat Agcy BRIN, Res Ctr Vaccine & Drug, Res Org Hlth, Cibinong, Indonesia
[2] Minist Marine Affairs & Fisheries, Inst Mariculture Res & Fisheries Extens, Agcy Marine & Fisheries Res & Human Resources, Jakarta, Indonesia
关键词
Antioxidant; anticancer; biological activities; nutritional value; sea cucumber; TRITERPENE GLYCOSIDES; ANTIOXIDANT CAPACITY; PHENOLIC CONTENTS; IN-VITRO; CYTOTOXICITY; COMPONENTS; GROWTH; GULF; ACID; ATRA;
D O I
10.1080/10498850.2022.2082902
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
The aim of this study was to investigate the production of H. scabra in an open pond culture system and to evaluate the nutritional value and biological activities. H scabra in this study was successfully grown with an average size 15.3 cm and weight 132.7 g after an eight month period. The H. scabra cultured was rich in protein content (73.41%). The extracts obtained from the soxhletation method showed potential antioxidant and anticancer activity against MDA-MB-231 breast cell cancer lines, with the greatest antioxidant activity of 5.97 +/- 0.95 TEAC (based on the ABTS method). The activity is related to the highest total flavonoid content (249.96 mg QE/100 g). The soxhlet and maceration extracts also showed potent cytotoxic activity against human breast cancer MDA-MB 231. These data indicated that by culturing H. scabra in an open pond system could provide a high quality of sea cucumber in terms of biomass yield and biological activity.
引用
收藏
页码:599 / 614
页数:16
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