Enantioselective addition of Et2Zn to aldehydes catalyzed by chiral aliphatic β-amino alcohols

被引：0

作者：

Shen, ZX ^{[1
]}

Xu, XN ^{[1
]}

Liu, XF ^{[1
]}

Zhang, LF ^{[1
]}

Zhang, YW ^{[1
]}

机构：

[1] Suzhou Univ, Dept Chem & Chem Engn, Suzhou 215006, Peoples R China

来源：

CHINESE JOURNAL OF CHEMISTRY | 2000年 / 18卷 / 04期

关键词：

enantioselective addition; beta-amino alcohol; enantioselectivity;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

This paper describes the preparation of two new optically active aliphatic beta-amino alcohols (R)-5,5-dimethyl-2(dimethylamino)-1,1-diphenyl-1-hexanol (1a) and (S)-8,8-dimethyl-2-(dimethylamino)-1,1-diphenyl-1-nonanol (Ib). They were synthesized by methylation of the corresponding beta-amino alcohols 2a and 2b. Compounds la and Ib catalyze the addition of diethylzinc to various aldehydes enantioselectively. The catalyst structure-enantioselectivity relationships were discussed.

引用

页码：582 / 584

页数：3

共 50 条

[1] Enantioselective addition of Et2Zn to aldehydes catalyzed by chi-ral aliphatic β-amino alcohols
沈宗旋
许学农
刘小峰
张丽芬
张雅文
Chinese Journal of Chemistry, 2000, (04) : 582 - 584
[2] Enantioselective alkynylations of aromatic and aliphatic aldehydes catalyzed by terpene derived chiral amino alcohols
Watts, CC
Thoniyot, P
Hirayama, LC
Romano, T
Singaram, B
TETRAHEDRON-ASYMMETRY, 2005, 16 (10) : 1829 - 1835
[3] SYNTHESIS OF A NEW LINEAR CHIRAL POLYMER BASED ON POLYBINAPHTHOLS AND ITS APPLICATION IN ENANTIOSELECTIVE ADDITION OF Et2Zn TO ALDEHYDES
Wu, Ling-lin
Zheng, Li-fei
Huang, Xiao-bo
Cheng, Yi-xiang
ACTA POLYMERICA SINICA, 2013, (06) : 802 - 810
[4] Highly Enantioselective Addition of Phenylethynylzinc to Aldehydes Catalyzed by Chiral Cyclopropane-Based Amino Alcohols
Zheng, Bing
Li, Zhiyuan
Liu, Feipeng
Wu, Yanhua
Shen, Junjian
Bian, Qinghua
Hou, Shicong
Wang, Ming
MOLECULES, 2013, 18 (12) : 15422 - 15433
[5] HIGHLY ENANTIOSELECTIVE ADDITION OF DIETHYLZINC TO ALDEHYDES CATALYZED BY CHIRAL S-AMINO-T-ALCOHOLS
SOAI, K
WATANABE, M
YAMAMOTO, A
YAMASHITA, T
JOURNAL OF MOLECULAR CATALYSIS, 1991, 64 (03): : L27 - L30
[6] Highly Enantioselective Addition of Diethylzinc to Aldehydes Catalyzed by Novel Chiral tert-Amino Alcohols
Zhang, Cong-hai
Yan, Sheng-jiao
Pan, Sheng-qiang
Huang, Rong
Lin, Jun
BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 2010, 31 (04): : 869 - 873
[7] Enantioselective alkynylations of aromatic and aliphatic aldehydes catalyzed by terpene-derived chiral amino alcohols.
Singaram, B
Watts, CC
Thoniyot, P
Hirayama, L
Romano, T
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2005, 229 : U570 - U570
[8] Asymmetric addition of diethylzinc to aldehydes catalyzed by chiral γ-amino alcohols
Xu, QY
Wu, TX
Pan, XF
CHINESE CHEMICAL LETTERS, 2001, 12 (12) : 1055 - 1056
[9] Asymmetric Addition of Diethylzinc to Aldehydes Catalyzed by Chiral γAmino Alcohols
Qian Yong XU
Chinese Chemical Letters, 2001, (12) : 1055 - 1056
[10] Enantioselective addition of phenylacetylene to ketones catalyzed by chiral amino alcohols
Ding Juan
Shen Zong-Xuan
Luo Xiao-Qing
Chen Wei-Yi
Zhang Ya-Wen
CHINESE JOURNAL OF CHEMISTRY, 2006, 24 (10) : 1285 - 1289

← 1 2 3 4 5 →