Neurodegeneration in Hepatic and Neurologic Wilson's Disease

被引：11
|
作者：
Viveiros, Andre [1 ,2 ]
Beliveau, Vincent [2 ,3 ]
Panzer, Marlene [1 ,2 ]
Schaefer, Benedikt [1 ,2 ]
Glodny, Bernhard [2 ,4 ]
Henninger, Benjamin [2 ,4 ]
Tilg, Herbert [1 ,2 ]
Zoller, Heinz [1 ,2 ]
Scherfler, Christoph [2 ,3 ]
机构：
[1] Med Univ, Dept Med 1, Anichstr 35, A-6020 Innsbruck, Austria
[2] Univ Hosp Innsbruck, Anichstr 35, A-6020 Innsbruck, Austria
[3] Med Univ, Dept Neurol, Innsbruck, Austria
[4] Med Univ, Dept Radiol, Innsbruck, Austria
来源：
HEPATOLOGY | 2021年 / 74卷 / 02期
关键词：
D O I：
10.1002/hep.31681
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Clinical presentation of Wilson disease (WD) includes hepatic and neurologic manifestations. This study compares subcortical brain regions by magnetic resonance imaging in patients with WD and without neurological symptoms. Distinct atrophy affecting the basal ganglia, accumbens, and hippocampus was present in neurological WD. Cerebellar atrophy was observed in hepatic WD without neurological symptoms. © 2020 The Authors. Hepatology published by Wiley Periodicals LLC on behalf of American Association for the Study of Liver Diseases.
引用
收藏
页码：1117 / 1120
页数：4
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