Case Management of Dengue: Lessons Learned

被引：32

作者：

Kalayanarooj, Siripen ^{[1
]}

Rothman, Alan L. ^{[2
,3
]}

Srikiatkhachorn, Anon ^{[1
,2
,3
]}

机构：

[1] Queen Sirikit Natl Inst Child Hlth, Dengue Unit, Bangkok, Thailand

[2] Univ Rhode Isl, Dept Cell & Mol Biol, 825 Chalkstone Ave, Providence, RI 02908 USA

[3] Univ Rhode Isl, Inst Immunol & Informat, 80 Washington St, Providence, RI 02903 USA

来源：

JOURNAL OF INFECTIOUS DISEASES | 2017年 / 215卷

基金：

英国医学研究理事会; 美国国家卫生研究院;

关键词：

dengue; plasma leakage; hemorrhage; case management; clinical care; case-fatality rate; HEMORRHAGIC-FEVER; DOUBLE-BLIND; SHOCK-SYNDROME; VIRUS-INFECTION; PLASMA LEAKAGE; IMMUNE ACTIVATION; DISEASE SEVERITY; ADULT PATIENTS; CHILDREN; THAILAND;

D O I：

10.1093/infdis/jiw609

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The global burden of dengue and its geographic distribution have increased over the past several decades. The introduction of dengue in new areas has often been accompanied by high case-fatality rates. Drawing on the experience in managing dengue cases at the Queen Sirikit National Institute of Child Health in Bangkok, Thailand, this article provides the authors' perspectives on key clinical lessons to improve dengue-related outcomes. Parallels between this clinical experience and outcomes reported in randomized controlled trials, results of efforts to disseminate practice recommendations, and suggestions for areas for further research are also discussed.

引用

页码：S79 / S88

页数：10

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