INSECT 2.0: a web-server for genome-wide cis-regulatory modules prediction

被引:13
|
作者
Gonzalo Parra, R. [1 ]
Rohr, Cristian O. [1 ]
Koile, Daniel [2 ]
Perez-Castro, Carolina [2 ]
Yankilevich, Patricio [2 ]
机构
[1] Univ Buenos Aires, Fac Ciencias Exactas & Nat, Buenos Aires, DF, Argentina
[2] Max Planck Gesell, CONICET, Partner Inst, Inst Invest Biomed Buenos Aires IBioBA, Godoy Cruz 2390,Buenos Aires C1425FQA, Buenos Aires, DF, Argentina
关键词
TRANSCRIPTION FACTORS; ORGANIZATION; MODELS;
D O I
10.1093/bioinformatics/btv726
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
INSECT is a user-friendly web server to predict the occurrence of Cis-Regulatory Modules (CRMs), which control gene expression. Here, we present a new release of INSECT which includes several new features, such as whole genome analysis, nucleosome occupancy predictions, and which provides additional links to third-party functional tools that complement user capabilities, CRM analysis and hypothesis construction. Improvements in the core implementation have led to a faster and more efficient tool. In addition, this new release introduces a new interface designed for a more integrative and dynamic user experience.
引用
收藏
页码:1229 / 1231
页数:3
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