Synthesis of 2-deoxy ribose related disaccharide nucleoside and its phosphoramidite

被引:1
|
作者
Ding, Yili [1 ]
Deng, Rilie [1 ]
Wang, Bingyun [1 ]
机构
[1] Foshan Univ, Life Sci Dept, Foshan 528000, Guangdong, Peoples R China
关键词
Disaccharide nucleoside; Phosphoramidite; Synthesis; 2-Deoxy ribose; Glycosylation; OLIGONUCLEOTIDES;
D O I
10.1016/j.tet.2017.05.052
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Synthesis of impurity reference compound of anti-tumor drug ISIS 183750 was achieved. In this process, a general method for synthesis of 2-deoxy ribosyl disaccharide nucleosides was established for the first time. (C) 2017 Elsevier Ltd. All rights reserved.
引用
收藏
页码:3848 / 3852
页数:5
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