Smart microfluidic electrochemical DNA sensors with signal processing circuits

A smart microfluidic DNA sensor with an integrated signal-processing circuit for electrochemical analysis has been successfully fabricated. The sensor comprises an integrated electrochemical sensing electrode, a microfluidic channel-type reactor, and operational amplifiers for electrochemical measurement. The microfluidic reactor employs a laminar flow principle. Generally, a relatively large and expensive system is necessary for electrochemical measurement. In the fabricated smart chip, signal-processing circuits for measuring cyclic-voltammogram characteristics are integrated, permitting cyclic-voltammograms to be successively measured, using only two simple sources of electrical power.