Biologically interesting chiral 3,4-disubstituted pyrrolidines from optically active hydroxycitric acid lactones

被引：32
|
作者：
Ibnusaud, I [1 ]
Thomas, G [1 ]
机构：
[1] Mahatma Gandhi Univ, Sch Chem Sci, Kottayam 686560, Kerala, India
来源：
TETRAHEDRON LETTERS | 2003年 / 44卷 / 06期
关键词：
D O I：
10.1016/S0040-4039(02)02781-8
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Starting with (2S,3S)-tetrahydro-3-hydroxy-5-oxo-2,3-furandicarboxylic acid (garcinia acid), isolated from the chiral pool, and alkyl amines, 3,4-disubstituted pyrrolidinediones, analogues of naturally occurring mescaline isocitrimidelactone, have been obtained in one-pot. These imides were subsequently converted into optically active pyrrolidines. (C) 2003 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：1247 / 1249
页数：3
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