Morphological Changes in Paraurethral Area after Introduction of Tissue Engineering Construct on the Basis of Adipose Tissue Stromal Cells

被引：5
|
作者：
Makarov, A. V. [1 ,2 ]
Arutyunyan, I. V. [1 ,3 ]
Bol'shakova, G. B. [2 ]
Volkov, A. V. [1 ,2 ]
Gol'dshtein, D. V. [1 ,2 ,3 ]
机构：
[1] ReMeTeks Co, Moscow, Russia
[2] Russian Acad Med Sci, Inst Human Morphol, Moscow, Russia
[3] Russian Acad Med Sci, Med Genet Res Ctr, Moscow, Russia
来源：
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2009年 / 148卷 / 04期
关键词：
multipotent stromal cells; connective tissue; tissue engineering construct; transplantation; 1-YEAR FOLLOW-UP; IN-VITRO; INCONTINENCE; TOXICITY;
D O I：
10.1007/s10517-010-0801-y
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
We studied morphological changes in the paraurethral area of Wistar rats after introduction of tissue engineering constructs on the basis of multipotent mesenchymal stem cells and gelatin sponge. The tissue engineering construct containing autologous culture of the stromal fraction of the adipose tissue was most effective. After introduction of this construct we observed more rapid degradation of the construct matrix and more intensive formation of collagen fibers.
引用
收藏
页码：719 / 724
页数：6
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