225Ac/213Bi generator based on inorganic sorbents

被引：12

作者：

Vasiliev, Aleksandr N. ^{[1
]}

Ermolaev, Stanislav, V ^{[1
]}

Lapshina, Elena, V ^{[1
]}

Zhuikov, Boris L. ^{[1
]}

Betenekov, Nikolay D. ^{[2
]}

机构：

[1] Russian Acad Sci, Inst Nucl Res, 60th October Anniversary Prospect 7a, Moscow 117312, Russia

[2] Yeltsin Ural Fed Univ, Ul Mira 19, Ekaterinburg 620002, Russia

来源：

RADIOCHIMICA ACTA | 2019年 / 107卷 / 12期

基金：

俄罗斯科学基金会;

关键词：

Ac-225/Bi-213; generator; isotope generator; alpha-therapy; inorganic sorbents; titanium and zirconium oxides; sorption; THORIUM TARGETS; CROSS-SECTIONS; ALPHA; BI-213; ACTINIUM-225; PROTONS; THERAPY; RA-223; AC-225; SYSTEM;

D O I：

10.1515/ract-2019-3137

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A scheme of an "inverse" generator based on an inorganic sorbent (annealed zirconium and yttrium mixture oxides) has been proposed and tested. The generator demonstrated high yield of the Bi-213 product (up to 97 % in 0.5 mL of eluate), high degree of purification from the actinium isotopes (up to 10(-2)% of initial Ac-225 in 3 M NaNO3 solution), as well as the products of Ac-227 decay, and low radiation impact on the sorbent. Application of circulating approach to the sorption of Bi-213 provides decreasing processing time to 5 min at higher yield of the product.

引用

页码：1203 / 1211

页数：9

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