Pd-catalyzed one-pot coupling of allylamines, activated alkenes, and unsaturated halides (or triflate):: an atom efficient synthesis of highly functionalized pyrrolidines

被引:17
|
作者
Martinon, L
Azoulay, S
Monteiro, N
Kündig, EP
Balme, G
机构
[1] Univ Lyon 1, CNRS, UMR 5181, Lab Chim Organ 1,CPE, F-69622 Villeurbanne, France
[2] Univ Geneva, Dept Organ Chem, CH-1211 Geneva, Switzerland
关键词
palladium; multicomponent reaction; carbocyclization; pyrrolidines;
D O I
10.1016/j.jorganchem.2004.07.039
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
A Pd-catalyzed three-component assembling of highly functionalized 4-benzyl-(and allyl-)pyrrolidines was achieved based on a combination of allyl amines, gem-diactivated alkenes, and unsaturated halides (or triflate). (C) 2004 Elsevier B.V. All rights reserved.
引用
收藏
页码:3831 / 3836
页数:6
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