Effects of Mn concentration on the ac magnetically induced heating characteristics of superparamagnetic MnxZn1-xFe2O4 nanoparticles for hyperthermia

被引：27
|
作者：
Jeun, Minhong [1 ]
Moon, Seung Je [1 ]
Kobayashi, Hiroki [2 ]
Shin, Hye Young [3 ]
Tomitaka, Asahi [2 ]
Kim, Yu Jeong [4 ]
Takemura, Yasushi [2 ]
Paek, Sun Ha [3 ]
Park, Ki Ho [4 ]
Chung, Kyung-Won [5 ]
Bae, Seongtae [1 ]
机构：
[1] Natl Univ Singapore, BML, Dept Elect & Comp Engn, Singapore 117576, Singapore
[2] Yokohama Natl Univ, Dept Elect & Comp Engn, Yokohama, Kanagawa 2408501, Japan
[3] Seoul Natl Univ, Coll Med, Dept Neurosurg, Inst Canc Res,Ischem Hypox Dis Inst, Seoul 110744, South Korea
[4] Seoul Natl Univ, Coll Med, Dept Ophthalmol, Seoul 110744, South Korea
[5] Daion Co Ltd, Inchon 405846, South Korea
来源：
APPLIED PHYSICS LETTERS | 2010年 / 96卷 / 20期
关键词：
biomedical materials; hyperthermia; manganese compounds; nanobiotechnology; nanoparticles; superparamagnetism; zinc compounds; ZN FERRITE; FUTURE;
D O I：
10.1063/1.3430043
中图分类号：
O59 [应用物理学];
学科分类号：
摘要：
The effects of Mn2+ cation concentration on the ac magnetically induced heating characteristics and the magnetic properties of superparamagnetic MnxZn1-xFe2O4 nanoparticles (SPNPs) were investigated to explore the biotechnical feasibility as a hyperthermia agent. Among the MnxZn1-xFe2O4 SPNPs, the Mn0.5Zn0.5Fe2O4 SPNP showed the highest ac magnetically induced heating temperature (Delta T-ac,T-mag), the highest specific absorption rate (SAR), and the highest biocompatibility. The higher out of phase susceptibility (chi('')(m)) value and the higher chemical stability systematically controlled by the replacement of Zn2+ cations by the Mn2+ cations on the A-site (tetrahedral site) are the primary physical reason for the promising biotechnical properties of Mn0.5Zn0.5Fe2O4 SPNP. (C) 2010 American Institute of Physics. [doi: 10.1063/1.3430043]
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页数：3
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