Pneumocystis jirovecii Pneumonia

被引：175

作者：

Catherinot, Emilie ^{[1
,2
]}

Lanternier, Fanny ^{[1
]}

Bougnoux, Marie-Elisabeth ^{[3
]}

Lecuit, Marc ^{[1
]}

Couderc, Louis-Jean ^{[2
]}

Lortholary, Olivier ^{[1
,4
]}

机构：

[1] Univ Paris 05, Hop Necker Enfants Malad, Ctr Infectiol Necker Pasteur, Serv Malad Infect & Trop, F-75015 Paris, France

[2] Univ Versailles St Quentin, Hop Foch, Serv Pneumol, Suresnes, France

[3] Univ Paris 05, Hop Necker Enfants Malad, Microbiol Serv, F-75015 Paris, France

[4] Inst Pasteur, Ctr Natl Reference Mycol & Antifong, Paris, France

来源：

INFECTIOUS DISEASE CLINICS OF NORTH AMERICA | 2010年 / 24卷 / 01期

关键词：

Pneumocystis jirovecii; AIDS; Pulmonary infections; Chemoprophylaxis; ACQUIRED-IMMUNODEFICIENCY-SYNDROME; HIV-INFECTED PATIENTS; RENAL-TRANSPLANT RECIPIENTS; REAL-TIME PCR; F-SP HOMINIS; PREVENTING OPPORTUNISTIC INFECTIONS; BRONCHOALVEOLAR LAVAGE SPECIMENS; CARINII DIHYDROPTEROATE SYNTHASE; OBSTRUCTIVE PULMONARY-DISEASE; TRIMETHOPRIM-SULFAMETHOXAZOLE;

D O I：

10.1016/j.idc.2009.10.010

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Pneumocystis jirovecii has gained attention during the last decade in the context of the AIDS epidemic and the increasing use of cytotoxic and immunosuppressive therapies. This article summarizes current knowledge on biology, pathophysiology, epidemiology, diagnosis, prevention, and treatment of pulmonary P jirovecii infection, with a particular focus on the evolving pathophysiology and epidemiology. Pneumocystis pneumonia still remains a severe opportunistic infection, associated with a high mortality rate.

引用

页码：107 / +

页数：33

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