Correction of haemorheological disturbances in myocardial infarction by diquertin and ascorbic acid

被引：13
|
作者：
Plotnikov, MB
Aliev, OI
Maslov, MJ
Vasiliev, AS
Tjukavkina, NA
机构：
[1] Russian Acad Med Sci, Ctr Sci, Inst Pharmacol, Lab Blood Circulat Pharmacol, Tomsk 634028, Russia
[2] IM Sechenov Med Acad, Dept Organ Chem, Moscow 105043, Russia
来源：
PHYTOTHERAPY RESEARCH | 2003年 / 17卷 / 01期
关键词：
diquertin; ascorbic acid; myocardial infarction; haemorheology;
D O I：
10.1002/ptr.1082
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
In a model of the high blood viscosity syndrome, developed after myocardial infarction in rats, it was observed that a therapy of a combination of diquertin (20 mg/kg) and ascorbic acid (50 mg/kg) for a period of 6 days, resulted in an improvement of haemorheological indices. The decrease in blood viscosity was primarily due to an improved deformability of erythrocytes, and to some extent, due to a decrease in the content of plasma fibrinogen and erythrocyte aggregation. Copyright (C) 2003 John Wiley Sons, Ltd.
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收藏
页码：86 / 88
页数：3
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