Regioselective Synthesis of Polyaza Pyrimidines and Polyaza Pyrazoles under One-Pot Multicomponent Reaction Conditions

被引：0
|
作者：
Singh, Okram Mukherjee [1 ]
Devi, Laishram Ronibala [1 ]
Lim, Ki Bum [2 ,3 ]
Lee, Sang-Gyeong [2 ,3 ]
机构：
[1] Manipur Univ, Dept Chem, Imphal 795003, Manipur, India
[2] Gyeongsang Natl Univ, Grad Sch Mol Mat & Nanochem, Dept Chem, Jinju 660701, South Korea
[3] Gyeongsang Natl Univ, Grad Sch Mol Mat & Nanochem, Res Inst Nat Sci, Jinju 660701, South Korea
来源：
JOURNAL OF HETEROCYCLIC CHEMISTRY | 2014年 / 51卷 / 05期
关键词：
OXO KETENE DITHIOACETALS; MOLECULAR-SCALE WIRES; FUNCTIONALIZED 2,6-OLIGOPYRIDINES; SUPRAMOLECULAR CHEMISTRY; COORDINATION ARRAYS; HETEROCYCLES; ENAMINONES; ROUTE; SALTS; S; N-ACETALS;
D O I：
10.1002/jhet.1781
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Convenient methods of synthesis of novel polyaza pyrimidines and polyaza pyrazoles have been described in this paper. The synthetic method is based on one-pot, three-component cyclocondensation of -oxoketene dithioacetals, 2,6-diaminopyridine, and guanidine/hydrazine. Polyaza S,N-acetals have been generated in situ by treating -oxoketene dithioacetals with 2,6-diaminopyridine in the presence of n-butyl lithium, which were subsequently treated with guanidine nitrate and hydrazine hydrate to afford polyaza pyrimidines and polyaza pyrazoles, respectively.
引用
收藏
页码：1340 / 1344
页数：5
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