Identification of 5-aminosalicylic acid, ciprofloxacin and azithromycin by abrasive stripping voltammetry

被引：49
|
作者：
Komorsky-Lovric, S
Nigovic, B
机构：
[1] Rudjer Boskovic Inst, Ctr Marine & Environm Res, Zagreb 10002, Croatia
[2] Univ Zagreb, Fac Pharm & Biochem, Zagreb 10000, Croatia
来源：
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | 2004年 / 36卷 / 01期
关键词：
abrasive stripping voltammetry; microcrystals; 5-aminosalicylic acid; ciprofloxacin; azithromycin;
D O I：
10.1016/j.jpba.2004.05.008
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Solid microparticles of 5-aminosalicylic acid, ciprofloxacin, and azithromycin were mechanically immobilized on the surface of the paraffin impregnated graphite electrode and investigated by square-wave and cyclic voltammetry in order to develop a method for their qualitative determination. 5-Aminosalicylic acid is oxidized at 0.540V in the quasireversible electrode reaction, which is followed by the chemical transformation of the product, while ciprofloxacin and azithromycin are oxidized at 1.2V and 0.94V, respectively, in totally irreversible electrode reactions. The detection of these drugs in commercial dosage formulations is reported. (C) 2004 Elsevier B.V. All rights reserved.
引用
收藏
页码：81 / 89
页数：9
相关论文
共 50 条
  • [21] DETERMINATION OF 5-AMINOSALICYLIC ACID IN PHARMACEUTICAL FORMULATIONS BY SQUARE WAVE VOLTAMMETRY AT PENCIL GRAPHITE ELECTRODES
    Uliana, Carolina V.
    Yamanaka, Hideko
    Garbellini, Gustavo S.
    Salazar-Banda, Giancarlo R.
    [J]. QUIMICA NOVA, 2010, 33 (04): : 964 - 967
  • [22] Duration of treatment with 5-aminosalicylic acid compounds
    T Moshkovska
    JF Mayberry
    [J]. World Journal of Gastroenterology, 2007, (32) : 4310 - 4315
  • [23] LUNG AND SKIN HYPERSENSITIVITY TO 5-AMINOSALICYLIC ACID
    LEGROS, V
    SAVEUSE, H
    LESUR, G
    BRION, N
    [J]. BRITISH MEDICAL JOURNAL, 1991, 302 (6782): : 970 - 970
  • [24] Further corroboration of the asthmagenicity of 5-aminosalicylic acid
    Seed, Martin
    Agius, Raymond
    [J]. OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, 2011, 68 (05) : 386 - 386
  • [25] HAIR LOSS AND 5-AMINOSALICYLIC ACID ENEMAS
    KUTTY, PK
    RAMAN, KRK
    HAWKEN, K
    BARROWMAN, JA
    [J]. ANNALS OF INTERNAL MEDICINE, 1982, 97 (05) : 785 - 786
  • [26] Baboon syndrome from 5-aminosalicylic acid
    Gallo, R
    Parodi, A
    [J]. CONTACT DERMATITIS, 2002, 46 (02) : 110 - 110
  • [27] Safety of topical 5-aminosalicylic acid in pregnancy
    Bell, CM
    Habal, FM
    [J]. AMERICAN JOURNAL OF GASTROENTEROLOGY, 1997, 92 (12): : 2201 - 2202
  • [28] Duration of treatment with 5-aminosalicylic acid compounds
    Moshkovska, T.
    Mayberry, J. F.
    [J]. WORLD JOURNAL OF GASTROENTEROLOGY, 2007, 13 (32) : 4310 - 4315
  • [29] INHIBITION OF ANTIBODY SECRETION BY 5-AMINOSALICYLIC ACID
    MACDERMOTT, RP
    SCHLOEMANN, SR
    BERTOVICH, MJ
    NASH, GS
    PETERS, M
    STENSON, WF
    [J]. GASTROENTEROLOGY, 1989, 96 (02) : 442 - 448
  • [30] 5-AMINOSALICYLIC ACID ENEMAS IN DISTAL COLITIS
    RAO, SSC
    [J]. GASTROENTEROLOGY, 1988, 95 (06) : 1698 - 1698
12345