Restricted tests for testing independence of time to failure and cause of failure in a competing-risks model

被引:9
|
作者
Dykstra, R
Kochar, S
Robertson, T
机构
[1] Univ Iowa, Dept Stat & Actuarial Sci, Iowa City, IA 52242 USA
[2] Indian Stat Inst, New Delhi 110016, India
关键词
isotonic regression; chi-bar-square distribution; likelihood-ratio dependence; multinomial distribution;
D O I
10.2307/3315673
中图分类号
O21 [概率论与数理统计]; C8 [统计学];
学科分类号
020208 ; 070103 ; 0714 ;
摘要
We consider the competing-risks problem without making any assumption concerning the independence of the risks. Maximum-likelihood estimates of the cause-specific hazard rates are obtained under the condition that their ratio is monotone. We also consider the likelihood-ratio test for testing the proportionality of two cause-specific hazard rates against the alternative that the ratio of these two hazard rates is monotonic. This testing problem is equivalent to testing independence against likelihood-ratio dependence of the time to failure and the cause of failure in the competing-risks setup. We allow for random censoring on the night. The asymptotic null distribution of the test statistic is obtained and is found to be of the chi-bar-square type. The problem is extended to the case of more than two risks. A numerical example is given to illustrate the procedure.
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页码:57 / 68
页数:12
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