Testing for independence in a competing risks model

被引:0
|
作者
Carling, K [1 ]
机构
[1] UNIV UPPSALA,DEPT STAT,S-75120 UPPSALA,SWEDEN
关键词
bivariate failure times; dependent competing risks; likelihood ratio test; bivariate mixing distributions; Monte Carlo simulations;
D O I
10.1016/0167-9473(96)00006-0
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
This paper examines the performance of the conventional likelihood ratio test when testing for independence between failure times in a competing risks framework. The dependence between failure times arises by stochastically related unobserved components. The unobserved components are estimated non-parametrically. Although the non-parametric method is appealing in empirical work, large-sample properties of the estimators are hard to come by analytically. This paper considers large-sample as well as small-sample properties of the likelihood ratio statistic by means of Monte Carlo simulations. The model is a dependent competing risks model of the mixed proportional hazard type. The failure times are Weibull distributed and the unobserved heterogeneity is generated by a bivariate normal. Simulations suggest that the distribution of the statistic is close to the chi(2) distribution for large sample sizes while for smaller sample sizes, the empirical distribution is more heavy-tailed than the chi(2) distribution.
引用
收藏
页码:527 / 535
页数:9
相关论文
共 50 条
  • [1] On Independence Of Competing Risks
    Dewan, Isha
    [J]. ADVANCES IN MATHEMATICAL MODELING FOR RELIABILITY, 2008, : 63 - 71
  • [2] Restricted tests for testing independence of time to failure and cause of failure in a competing-risks model
    Dykstra, R
    Kochar, S
    Robertson, T
    [J]. CANADIAN JOURNAL OF STATISTICS-REVUE CANADIENNE DE STATISTIQUE, 1998, 26 (01): : 57 - 68
  • [3] COMPETING RISKS WITHOUT INDEPENDENCE
    COHEN, JE
    LIU, L
    [J]. POPULATION INDEX, 1985, 51 (03) : 449 - 449
  • [4] TESTING THE INDEPENDENCE OF COMPETING RISKS - AN APPLICATION TO THE ANALYSIS OF BREAST-CANCER RECURRENCE
    ASSELAIN, B
    FOURQUET, A
    HOANG, T
    MYASNIKOVA, C
    YAKOVLEV, A
    [J]. BIOMETRICAL JOURNAL, 1994, 36 (04) : 465 - 473
  • [5] INDEPENDENCE OF TIME AND CAUSE OF FAILURE IN THE MULTIPLE DEPENDENT COMPETING RISKS MODEL
    KOCHAR, SC
    PROSCHAN, F
    [J]. STATISTICA SINICA, 1991, 1 (01) : 295 - 299
  • [6] Score tests for independence in parametric competing risks models
    Mériem Saïd
    Nadia Ghazzali
    Louis-Paul Rivest
    [J]. TEST, 2007, 16 : 547 - 564
  • [7] A Test for Independence of Competing Risks with Discrete Failure Times
    Crowder M.
    [J]. Lifetime Data Analysis, 1997, 3 (3) : 215 - 223
  • [8] Score tests for independence in semiparametric competing risks models
    Mériem Saïd
    Nadia Ghazzali
    Louis-Paul Rivest
    [J]. Lifetime Data Analysis, 2009, 15 : 413 - 440
  • [9] Score tests for independence in semiparametric competing risks models
    Said, Meriem
    Ghazzali, Nadia
    Rivest, Louis-Paul
    [J]. LIFETIME DATA ANALYSIS, 2009, 15 (04) : 413 - 440
  • [10] Score tests for independence in parametric competing risks models
    Said, Meriem
    Ghazzali, Nadia
    Rivest, Louis-Paul
    [J]. TEST, 2007, 16 (03) : 547 - 564