Microwave-assisted catalyst-free synthesis of tetrasubstituted pyrroles using dialkyl acetylenedicarboxylates and monophenacylanilines

被引:11
|
作者
Mariappan, Arumugam [1 ]
Rajaguru, Kandasamy [2 ]
Muthusubramanian, Shanmugam [1 ]
Bhuvanesh, Nattamai [2 ]
机构
[1] Madurai Kamaraj Univ, Sch Chem, Dept Organ Chem, Madurai 625021, Tamil Nadu, India
[2] Texas A&M Univ, Dept Chem, Xray Diffract Lab, College Stn, TX 77843 USA
关键词
Axial chirality; diethylacetylene dicarboxylate; microwave synthesis; polysubstituted pyrrole; HIGHLY SUBSTITUTED PYRROLES; GRAM-POSITIVE BACTERIA; ONE-POT SYNTHESIS; POLYSUBSTITUTED PYRROLES; REGIOSELECTIVE SYNTHESIS; EFFICIENT; AGENTS; CYCLOADDITION; ROSEOPHILIN; DERIVATIVES;
D O I
10.1080/00397911.2016.1176201
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
An efficient catalyst-free microwave-assisted synthesis of tetrasubstituted pyrroles using dialkyl acetylenedicarboxylates and substituted monophenacylanilines has been developed. Axial chirality has been noticed in some N-(-naphthyl/2-isopropylphenyl)-2,3-dicarbethoxy-4-arylpyrroles, but not with N-aryl-2,3-dicarbethoxy-4-(-naphthyl)pyrrole.
引用
收藏
页码:805 / 812
页数:8
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