ELECTROCHEMICAL STUDIES USING ACTIVATED GLASSY CARBON. I. MELOXICAM

The meloxicam was investigated in water-methanol solution by using cyclic voltammetry (CV) at anodically activated GCE. Two different times for application of the anodic activation electrode potential were used and six different times for application of three different accumulation electrode potentials were used in each case in order to obtain better cyclic voltammetric behaviour of meloxicam in comparison with that at inactivated GCE. It results an enhancement of the electron transfer ability to anodically activated GCE surface leading to a better electrochemical response (much better defined and more stable peak currents) regarding both peak current heights, which are higher, and peak potentials, which are anticipated, in comparison with the behaviour of meloxicam at inactivated bare GCE. The peak current ratio, defined as r(pa) I-pa,I-act/I-pa,I-inact, increases with increasing accumulation time for each activation potential used and for each accumulation electrode potential used. A change in the electrode mechanism from diffusion control (at bare GCE) to adsorption control (at anodically activated GCE) occurs.