One-Step Synthesis of Substituted Benzofurans from ortho- Alkenylphenols via Palladium-Catalyzed CH Functionalization

被引：40

作者：

Yang, Dejun ^{[1
]}

Zhu, Yifei ^{[1
]}

Yang, Na ^{[1
]}

Jiang, Qiangqiang ^{[1
]}

Liu, Renhua ^{[1
]}

机构：

[1] E China Univ Sci & Technol, Sch Pharm, 130 Meilong Rd, Shanghai 200237, Peoples R China

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2016年 / 358卷 / 11期

基金：

中国国家自然科学基金;

关键词：

acceptorless dehydrogenation; benzofurans; CH functionalization; oxidant-free conditions; palladium; ALCOHOL DEHYDROGENATION; H FUNCTIONALIZATION; SECONDARY ALCOHOLS; PHENOLS; DERIVATIVES; HYDROGENATION; LIGAND; IRON; H-2; ARYLBENZOFURAN;

D O I：

10.1002/adsc.201600082

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A dehydrogenative oxygenation of C(sp(2))H bonds with intramolecular phenolic hydroxy groups has been developed, which provides a straightforward and concise access to structurally diversely benzofurans from ortho-alkenylphenols. The reaction is catalyzed by palladium on carbon (Pd/C) without any oxidants and sacrificing hydrogen acceptors.

引用

页码：1731 / 1735

页数：5

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