The generation of GLP-grade human embryonic stem cell banks from four clinical-grade cell lines for preclinical research

被引：12
|
作者：
Sivarajah, Shirani [2 ,5 ]
Raj, Grace Selva [2 ]
Mathews, Adam Joshua Varughese [2 ]
Sahib, Norliza Binte Esmail [2 ]
Hwang, Wei Sek [4 ]
Crook, Jeremy Micah [1 ,2 ,3 ]
机构：
[1] OBrien Inst, Melbourne, Vic 3065, Australia
[2] ASTAR, Singapore Stem Cell Bank, Singapore Stem Cell Consortium, Singapore, Singapore
[3] ASTAR, Stem Cell Dis Models Lab, Inst Med Biol, Singapore, Singapore
[4] Kandang Kerbau Hosp, Singapore, Singapore
[5] Cytentia Australian Stem Cell Bank, Melbourne, Vic, Australia
来源：
IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL | 2010年 / 46卷 / 3-4期
关键词：
Human embryonic stem cells; Good laboratory practice; Banks; Clinical grade; Research grade;
D O I：
10.1007/s11626-010-9287-1
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The Singapore Stem Cell Bank has generated human embryonic stem cell banks from clinical-grade cell lines ESI-017, ESI-035, ESI-049, and ESI-053. All banks were prepared and characterized according to principles of Good Laboratory Practice for quality assurance. Importantly, each cell line has clearly documented and approved ethical provenance and meets recognized standards for performance and safety. The banks are intended to facilitate the translation of stem cell research to clinical medicine by enabling early phase research and development with high-quality, low-cost cells that are also available as clinical-grade stocks.
引用
收藏
页码：210 / 216
页数：7
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