Evaluation of antibacterial activity against Candida albicans according to the dosage of various denture cleansers

PURPOSE. The purpose of this study is to compare the antibacterial activity of currently purchasable denture cleansers against Candida albicans. MATERIALS AND METHODS : This study used tablet-type denture cleansers, Polident (R), Coolingdent (R) and Fittydent (R), along with liquid denture cleansers, Hexamedine (R), Listerine (R) and Apple vinegar (R). The antibacterial activities of denture cleansers were evaluated based on the number of C. albicans and concentrations of the denture cleansers. RESULTS. In the 0.5 x 10(6) cfu/ml culture medium, the C. albicans' death rate of Polident. was significantly lower than those of Fittydent (R), Hexamedine (R), Listerine (R), and Apple vinegar (R)(P <.05). In the 0.5 x 10(7) cfu/, the C. albicans' death rates of Polident (R) and Coolingdent (R) were significantly lower than those of Fittydent (R), Hexamedine (R), Listerine (R) and Apple vinegar (R)(P <.05). The C. albicans' death rates of Polident (R) and Coolingdent (R) were significantly decreased at 0.02 g and 0.01 g. The C. albicans' death rate of Fittydent (R) was significantly decreased at 0.005 g (P <.05). The C. albicans' death rate of Hexamedine (R) was significantly decreased at 1/16 dilution. The C. albicans' death rate of Listerine (R) was decreased at 1/8 dilution, and the antibacterial activity of Apple vinegar (R) was decreased at 1/4 dilution (P <.05). CONCLUSION. As the number of C. albicans increased, the antibacterial activities of the denture cleansers decrease. In the tablet-type denture cleanser, all denture cleansers showed 100% C. albicans' death rate when used at a dose of 1 tablet. One denture cleanser showed the same antibacterial effect with only 1/3 of a tablet. In the liquid type denture cleanser, the level of dilution required was different for each denture cleanser.