SIMULATION OF MAGNETIC NANOPARTICLES IN BLOOD FLOW FOR MAGNETIC DRUG TARGETING APPLICATIONS

被引：1
|
作者：
Slabu, I [1 ,2 ]
Roeth, A. [3 ]
Guentherodt, G. [2 ]
Schmitz-Rode, T. [1 ]
Baumann, M. [1 ]
机构：
[1] Rhein Westfal TH Aachen, Helmholtz Inst, Fac Med, Appl Med Engn, Aachen, Germany
[2] Rhein Westfal TH Aachen, Phys Inst 2, Aachen, Germany
[3] Univ Hosp Aachen, Dept Gen Visceral & Transplantat Surg, Aachen, Germany
来源：
BIOMEDICAL ENGINEERING-BIOMEDIZINISCHE TECHNIK | 2013年 / 58卷
关键词：
SPIO; FEM; magnetic drug targeting;
D O I：
10.1515/bmt-2013-4039
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
A new magnetic drug targeting model of placing an array of permanent magnets and coils inside hollow organs of the body was developed. This gives the possibility to target e. g. prostate carcinoma, oesophagus adenocarcinoma or bile duct Klatskin tumours with drugs bounded to magnetic nanoparticles. The targeting model uses FEM based simulations and describes the interaction of an external magnetic field with single suspended superparamagnetic iron oxide (SPIO) nanoparticles in blood flow, thereby, quantifying the amount of the accumulated SPIO at a vessel wall.
引用
收藏
页数：2
相关论文
共 50 条
  • [1] The flow of magnetic nanoparticles in magnetic drug targeting
    Kayal, Sibnath
    Bandyopadhyay, Dipankar
    Mandal, Tapas Kumar
    Ramanujan, Raju V.
    RSC ADVANCES, 2011, 1 (02) : 238 - 246
  • [2] Capture Efficiency of Biocompatible Magnetic Nanoparticles in Arterial Flow: A Computer Simulation for Magnetic Drug Targeting
    Lunnoo, Thodsaphon
    Puangmali, Theerapong
    NANOSCALE RESEARCH LETTERS, 2015, 10
  • [3] Capture Efficiency of Biocompatible Magnetic Nanoparticles in Arterial Flow: A Computer Simulation for Magnetic Drug Targeting
    Thodsaphon Lunnoo
    Theerapong Puangmali
    Nanoscale Research Letters, 2015, 10
  • [4] Magnetic nanoparticles for magnetic drug targeting
    Lyer, Stefan
    Singh, Raminder
    Tietze, Rainer
    Alexiou, Christoph
    BIOMEDICAL ENGINEERING-BIOMEDIZINISCHE TECHNIK, 2015, 60 (05): : 465 - 475
  • [5] Magnetic Particle Spectroscopy to Determine the Magnetic Drug Targeting Efficiency of Different Magnetic Nanoparticles in a Flow Phantom
    Radon, Patricia
    Liebl, Maik
    Poempner, Nadine
    Stapf, Marcus
    Wiekhorst, Frank
    Gitter, Kurt
    Hilger, Ingrid
    Odenbach, Stefan
    Trahms, Lutz
    IEEE TRANSACTIONS ON MAGNETICS, 2015, 51 (02) : 6000104
  • [6] Trajectory Simulation of Magnetic Nanoparticles in the Blood Vessel for the Magnetic Targeted-drug Delivery
    Feng, Jie
    Zhang, Ruilin
    Qu, Yanan
    Geng, Ping
    Qi, Shouliang
    MATERIALS PROCESSING AND MANUFACTURING III, PTS 1-4, 2013, 753-755 : 988 - +
  • [7] Modeling and simulation of blood flow with magnetic nanoparticles as carrier for targeted drug delivery in the stenosed artery
    Majee, Sreeparna
    Shit, G. C.
    EUROPEAN JOURNAL OF MECHANICS B-FLUIDS, 2020, 83 : 42 - 57
  • [8] Clinical applications of magnetic drug targeting
    Lübbe, AS
    Alexiou, C
    Bergemann, C
    JOURNAL OF SURGICAL RESEARCH, 2001, 95 (02) : 200 - 206
  • [9] Numerical Investigation of Magnetic Nanoparticles Trajectories for Magnetic Drug Targeting
    Shazri, Syireen
    Idres, Moumen
    3RD INTERNATIONAL CONFERENCE ON MECHANICAL, AUTOMOTIVE AND AEROSPACE ENGINEERING 2016, 2017, 184
  • [10] Analyzing hydrodynamics of magnetic nanoparticles for magnetic targeting drug delivery
    Liu, Handan
    Wang, Shigang
    Liang, Qinghua
    JOURNAL OF BIOTECHNOLOGY, 2008, 136 : S95 - S96
12345