Vinorelbine plus low-dose cisplatinum with concomitant radiotherapy for the treatment of locally advanced or inoperable non-metastasized non-small-cell lung cancer (stage I-IIIB): a phase II study

被引:5
|
作者
Winterhalder, R
Deschler-Marini, S
Landmann, C
Kann, R
Passweg, J
Herrmann, R
Pless, M
机构
[1] Univ Basel Hosp, Dept Oncol, CH-4031 Basel, Switzerland
[2] Univ Basel Hosp, Dept Radiat Oncol, CH-4031 Basel, Switzerland
[3] Univ Basel Hosp, Dept Hematol, CH-4031 Basel, Switzerland
关键词
low-dose cisplatin and weekly vinorelbine; concomitant chemoradiation; stage IIIBNSCLC;
D O I
10.1016/j.radonc.2004.06.009
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
In a phase II study. we assessed the toxicity and efficacy of daily low-dose cisplatin (6 mg/m(2)) and weekly vinorelbine (15 mg/m(2)) with concurrent thoracic irradiation (60 Gy) for locally advanced non-metastasized non-small-cell lung cancer. The overall response rate was 65%, complete response 12% and the median overall survival was 64 weeks. (C) 2004 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:321 / 324
页数:4
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