Effectiveness of image-guided radiotherapy for laryngeal sparing in head and neck cancer

被引：22

作者：

Nguyen, Nam P. ^{[1
]}

Ceizyk, Misty ^{[1
]}

Vos, Paul ^{[2
]}

Vinh-Hung, Vincent ^{[3
]}

Davis, Rick ^{[1
]}

Desai, Anand ^{[1
]}

Abraham, Dave ^{[1
]}

Krafft, Shane P. ^{[1
]}

Jang, Siyoung ^{[1
]}

Watchman, Christopher J. ^{[1
]}

Ewell, Lars ^{[1
]}

Hamilton, Russ ^{[1
]}

Smith-Raymond, Lexie ^{[1
]}

机构：

[1] Univ Arizona, Dept Radiat Oncol, Tucson, AZ 85724 USA

[2] E Carolina Univ, Greenville, NC USA

[3] Univ Hosp Geneva, Dept Radiat Oncol, Geneva, Switzerland

来源：

ORAL ONCOLOGY | 2010年 / 46卷 / 04期

关键词：

Head and neck cancer; IGRT; Laryngeal sparing; INTENSITY-MODULATED RADIOTHERAPY; RADIATION-THERAPY; HELICAL TOMOTHERAPY; NASOPHARYNGEAL CARCINOMA; IMRT; DYSPHAGIA; CHEMORADIATION; FIELD;

D O I：

10.1016/j.oraloncology.2010.01.010

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We would like to compare the effectiveness of image-guided (IGRT) and intensity-modulated (IMRT) radiotherapy to spare the larynx in head and neck cancer patients. A retrospective review of 48 patients undergoing radiation for non-laryngeal and non-hypopharyngeal head and neck cancers. Mean laryngeal and hypopharyngeal dose was compared between 11 patients treated with IMRT and 37 patients treated with IGRT. Mean laryngeal dose was, respectively, 41.2 Gy and 22.8 Gy for the IMRT and IGRT technique (p < 0.001). The radiation dose to the middle and inferior pharyngeal muscles was also significantly reduced with the IGRT technique. Mean pharyngeal dose was, respectively, 52 Gy and 26 Gy for the IMRT and IGRT technique (p = 0.0001). Laryngeal sparing IGRT technique for head and neck cancer minimizes radiotherapy dose to the larynx and pharynx without sacrificing target coverage, even in the presence of neck lymph nodes. (C) 2010 Elsevier Ltd. All rights reserved.

引用

页码：283 / 286

页数：4

共 50 条

[1] Variation of Neck Position With Image-guided Radiotherapy For Head And Neck Cancer
Ove, Roger
Cavalieri, Ronaldo
Noble, Darin
Russo, Suzanne M.
AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS, 2012, 35 (01): : 1 - 5
[2] Image-guided radiotherapy for head and neck carcinoma
Beddok, A.
Blanchard, P.
CANCER RADIOTHERAPIE, 2018, 22 (6-7): : 617 - 621
[3] THE POTENTIAL OF IMAGE-GUIDED RADIOTHERAPY FOR NORMAL ORGANS SPARING IN PATIENTS WITH LOCALLY ADVANCED HEAD AND NECK CANCER
Nguyen, Nam P.
Chi, Alexander
Vinh-Hung, Vincent
Gorobets, Olena
Bose, Satya
Karlsson, Ulf
ANTICANCER RESEARCH, 2014, 34 (10) : 6080 - +
[4] Image-guided radiotherapy for local y advanced head and neck cancer
Nguyen, Nam P.
Kratz, Sarah
Lemanski, Claire
Vock, Jacqueline
Vinh-Hung, Vincent
Gorobete, Olena
Chi, Alexander
Almeida, Fable
Betz, Michael
Khan, Rihan
Godinez, Juan
Karlsson, Ulf
Ampil, Fred
FRONTIERS IN ONCOLOGY, 2013, 3
[5] Image-guided radiotherapy in head-and-neck oncology
Balermpas, Panagiotis
ONKOLOGIE, 2023, 29 (01): : 45 - 50
[6] Recent Advances in Image-Guided Radiotherapy for Head and Neck Carcinoma
Nath, Sameer K.
Simpson, Daniel R.
Rose, Brent S.
Sandhu, Ajay P.
JOURNAL OF ONCOLOGY, 2009, 2009
[7] Image-guided elective neck irradiation in head and neck cancer
Al-Mamgani, A.
RADIOTHERAPY AND ONCOLOGY, 2019, 133 : S239 - S239
[8] Reirradiation using robotic image-guided stereotactic radiotherapy of recurrent head and neck cancer
Yamazaki, Hideya
Ogita, Mikio
Himei, Kengo
Nakamura, Satoaki
Suzuki, Gen
Yoshida, Ken
Kotsuma, Tadayuki
Yoshioka, Yasuo
JOURNAL OF RADIATION RESEARCH, 2016, 57 (03) : 288 - 293
[9] Dosimetric impact of setup errors in head and neck cancer patients treated by image-guided radiotherapy
Kaur, Inderjit
Rawat, Sheh
Ahlawat, Parveen
Kakria, Anjali
Gupta, Gourav
Saxena, Upasna
Mishra, Manindra Bhushan
JOURNAL OF MEDICAL PHYSICS, 2016, 41 (02) : 144 - 148
[10] Image-guided Biologically Adaptive Therapy for Head and Neck Cancer
Guerrero, M.
Carlson, D. J.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2019, 105 (01): : E793 - E793

← 1 2 3 4 5 →