Synthetic studies on tetrazomine:: lipase PS resolution of racemic cis-β-hydroxypipecolic acid

被引：32
|
作者：
Scott, JD [1 ]
Williams, RM [1 ]
机构：
[1] Colorado State Univ, Dept Chem, Ft Collins, CO 80523 USA
来源：
TETRAHEDRON LETTERS | 2000年 / 41卷 / 44期
基金：
美国国家卫生研究院;
关键词：
D O I：
10.1016/S0040-4039(00)01527-6
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient enzymatic resolution of racemic cis-beta -hydroxypipecolic acid is described affording both the (2S,3R) and (2R,3S) protected amino acids in good yield and high enantiomeric ratios. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：8413 / 8416
页数：4
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