In light of the reality and importance of hospitals in health networks and the several problems and difficulties involved in management and assistance of these health services, reflections were developed over the possibilities of giving attention to quality, resolutive and humanized hospital health care based on the integrality and singularity, within the scope of the Brazilian Unified Health System (UHS), by conducting qualitative, theoretical, bibliographic and documentary research. Considering the complex thinking, axes of reflection were developed, and from those, flows of interactivity and focuses of look direction. There were stablished, as lines of reflection, the hospital historical-social constitution, the health humanization and management; as interactivity flows, permeating among and through the axes, the possibilities of humanized hospital management and assistance and of health practices in the hospital based on the interlocution among the popular, cultural, social and individual dimensions, with the scientific, technical and bio-medical ones. The focuses of look direction involved religiosity, singular therapeutic project, and integrative and complementary practices - specifically the use of medicinal plants and phytotherapy - in the context of hospital care at UHS. The metonymic directions were related to the possibilities of constituting hospitals, with resolutive and quality health attention, based on humanized management and assistance, with a dialogue of practices and knowledge beyond the legitimized and standardized in health.