Synthesis of 4-phenyl-1-(2-thienyl)-2,3,4,9-tetrahydro-1H-β-carboline

被引：2
|
作者：
Semenov, B. B.
Novikov, K. A.
Kachala, V. V.
Azev, V. N.
机构：
[1] DI Mendeleev Russian Chem Engn Univ, Moscow, Russia
[2] Russian Acad Sci, Inst Organ Chem, Moscow, Russia
[3] Tufts Univ, Medford, MA 02155 USA
来源：
CHEMISTRY OF NATURAL COMPOUNDS | 2006年 / 42卷 / 05期
关键词：
beta-carbolines; Pictet-Spengler reaction; beta-phenyltryptamine; GABA-receptors;
D O I：
10.1007/s10600-006-0218-z
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The Pictet-Spengler reaction involving beta-phenyltryptamine was shown to be diastereo-specific with formation primarily of the (1S*,4R*) diastereomer of 4-phenyl-1-(2-thienyl)-2,3,4,9-tetrahydro-1H-beta-carboline, a compound with potential GABA-receptor activity.
引用
收藏
页码：582 / 584
页数：3
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