Synthesis of 4-phenyl-1-(2-thienyl)-2,3,4,9-tetrahydro-1H-β-carboline

被引：2

作者：

Semenov, B. B.

Novikov, K. A.

Kachala, V. V.

Azev, V. N.

机构：

[1] DI Mendeleev Russian Chem Engn Univ, Moscow, Russia

[2] Russian Acad Sci, Inst Organ Chem, Moscow, Russia

[3] Tufts Univ, Medford, MA 02155 USA

来源：

CHEMISTRY OF NATURAL COMPOUNDS | 2006年 / 42卷 / 05期

关键词：

beta-carbolines; Pictet-Spengler reaction; beta-phenyltryptamine; GABA-receptors;

D O I：

10.1007/s10600-006-0218-z

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The Pictet-Spengler reaction involving beta-phenyltryptamine was shown to be diastereo-specific with formation primarily of the (1S*,4R*) diastereomer of 4-phenyl-1-(2-thienyl)-2,3,4,9-tetrahydro-1H-beta-carboline, a compound with potential GABA-receptor activity.

引用

页码：582 / 584

页数：3

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