Menopausal Hormone Treatment in Postmenopausal Women: Risks and Benefits

被引：5
|
作者：
Dous, George V. [1 ]
Grodman, Richard [1 ]
Mornan, Adenieki [1 ]
Otterbeck, Philip [1 ]
Grigos, Angela [1 ]
机构：
[1] Univ Richmond, Med Ctr, Dept Med Cardiol & Endocrinol, Staten Isl, NY 10314 USA
来源：
SOUTHERN MEDICAL JOURNAL | 2014年 / 107卷 / 11期
关键词：
coronary artery disease; estrogen; postmenopausal; progesterone; CARDIOVASCULAR-DISEASE PREVENTION; CORONARY-ARTERY ATHEROSCLEROSIS; ESTROGEN REPLACEMENT; NITRIC-OXIDE; HEALTH OUTCOMES; THERAPY; PROGESTERONE; ESTRADIOL; HEART; PROGRESSION;
D O I：
10.14423/SMJ.0000000000000192
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Our objectives in this review were to examine the relevant menopausal hormone treatment (MHT) trials in postmenopausal women during the past 3 decades, provide an insight analysis of these studies from a clinical point of view, determine the efficacy and applicability of hormone therapy in the prevention of cardiovascular diseases, and provide suggestions on the use of MHT as a cardiovascular disease prophylaxis based on the available data. MHT may have a more complicated role in cardiovascular protection, and there is a need for further research to elucidate the dose and type of estrogen, its route of administration, the time of MHT initiation, and the preventive role of MHT in women's health.
引用
收藏
页码：689 / 695
页数：7
相关论文
共 50 条
  • [31] Menopausal hormone therapy and the risk of cataracts in postmenopausal women in South Korea
    Yuk, Jin-Sung
    Park, Jae Yong
    Sim, Ha Eun
    Hwang, Je Hyung
    OPHTHALMIC AND PHYSIOLOGICAL OPTICS, 2023, 43 (02) : 254 - 262
  • [32] Relationship between menopausal hormone therapy and incidence of fractures in postmenopausal women
    Kim, H.
    Kang, M. J.
    Baek, J. K.
    Lee, J. K.
    Choi, E. A.
    Yun, B. H.
    Kim, E. H.
    Seo, S. K.
    CLIMACTERIC, 2023, : 165 - 170
  • [33] REPRODUCTIVE ENDOCRINOLOGY Postmenopausal hormone therapy: risks versus benefits reassessed
    Simon, James A.
    NATURE REVIEWS ENDOCRINOLOGY, 2010, 6 (12) : 661 - 663
  • [34] Hormone therapy in the postmenopausal years: considering benefits and risks in clinical practice
    Genazzani, Andrea R.
    Monteleone, Patrizia
    Giannini, Andrea
    Simoncini, Tommaso
    HUMAN REPRODUCTION UPDATE, 2021, 27 (06) : 1115 - 1150
  • [35] Menopausal hormone therapy and the risk of cataract in postmenopausal women in South Korea
    Sim, Haeun
    Jeong, Jeonga
    Kang, Min Ji
    Hwang, Jehyung
    ACTA OPHTHALMOLOGICA, 2022, 100
  • [36] ESTROGEN USE IN POST-MENOPAUSAL WOMEN - COSTS, RISKS, AND BENEFITS
    WEINSTEIN, MC
    NEW ENGLAND JOURNAL OF MEDICINE, 1980, 303 (06): : 308 - 316
  • [37] Hormone replacement therapy: the risks and benefits of treatment
    Hardie, C.
    Bain, C.
    Walters, M.
    JOURNAL OF THE ROYAL COLLEGE OF PHYSICIANS OF EDINBURGH, 2009, 39 (04): : 324 - 326
  • [38] The benefits and risks of menopause hormone therapy for the cardiovascular system in postmenopausal women: a systematic review and meta-analysis
    Gu, Yimeng
    Han, Fangfang
    Xue, Mei
    Wang, Miyuan
    Huang, Yuxiao
    BMC WOMENS HEALTH, 2024, 24 (01)
  • [39] The benefits and risks of menopause hormone therapy for the cardiovascular system in postmenopausal women: a systematic review and meta-analysis
    Yimeng Gu
    Fangfang Han
    Mei Xue
    Miyuan Wang
    Yuxiao Huang
    BMC Women's Health, 24
  • [40] Randomized Trial Evaluation of the Benefits and Risks of Menopausal Hormone Therapy Among Women 50-59 Years of Age
    Prentice, Ross L.
    Aragaki, Aaron K.
    Chlebowski, Rowan T.
    Rossouw, Jacques E.
    Anderson, Garnet L.
    Stefanick, Marcia L.
    Wactawski-Wende, Jean
    Kuller, Lewis H.
    Wallace, Robert
    Johnson, Karen C.
    Shadyab, Aladdin H.
    Gass, Margery
    Manson, JoAnn E.
    AMERICAN JOURNAL OF EPIDEMIOLOGY, 2021, 190 (03) : 365 - 375
12345