Value of preoperative prothrombin time partial thromboplastin time as a predictor of postoperative hemorrhage in pediatric patients undergoing tonsillectomy
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作者:
Howells, RC
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W Virginia Univ, Sch Med, Dept Otolaryngol Head & Neck Surg, Morgantown, WV 26506 USAW Virginia Univ, Sch Med, Dept Otolaryngol Head & Neck Surg, Morgantown, WV 26506 USA
Howells, RC
[1
]
Wax, MK
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W Virginia Univ, Sch Med, Dept Otolaryngol Head & Neck Surg, Morgantown, WV 26506 USAW Virginia Univ, Sch Med, Dept Otolaryngol Head & Neck Surg, Morgantown, WV 26506 USA
Wax, MK
[1
]
Ramadan, HH
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W Virginia Univ, Sch Med, Dept Otolaryngol Head & Neck Surg, Morgantown, WV 26506 USAW Virginia Univ, Sch Med, Dept Otolaryngol Head & Neck Surg, Morgantown, WV 26506 USA
Ramadan, HH
[1
]
机构:
[1] W Virginia Univ, Sch Med, Dept Otolaryngol Head & Neck Surg, Morgantown, WV 26506 USA
OBJECTIVE: Hemorrhage after tonsillectomy is a potentially lethal complication. Preoperative assessment consisting of prothrombin time (PT) and activated partial thromboplastin time (PTT) has been used to identify patients at risk for hemorrhage after tonsillectomy and adenoidectomy. We sought to assess the value of PT/PTT screening as a predictor of posttonsillectomy hemorrhage. DESIGN: A retrospective chart review was carried out with a minimum of 1 month follow-up. SETTING: Tertiary academic referral center. PATIENTS: Between January 1992 and June 1995, 382 patients undergoing tonsillectomy were examined; 339 patients with a minimum of 1 month follow-up were reviewed for this study. MAIN OUTCOME MEASURE: Normal and prolonged PT/PTT Values were examined. Bleeding in the intraoperative, immediate postoperative, and delayed phases of healing was examined. RESULTS:Two-hundred and twenty-two patients had normal PT/PTT, 39 had prolonged PT/PTT, and 78 had no preoperative studies performed. Bleeding occurred in 2.7%, 2.6%, and 3.3%, respectively, of patients. Eight patients had positive family histories of bleeding tendencies. One patient (12.5%) with a normal PT/PTT experienced a delayed posttonsillectomy bleed. Of 39 patients with abnormal coagulation studies, 30 were borderline elevations with no repeat studies done; one patient experienced postoperative hemorrhage. Nine abnormal results were repeated; three returned to normal, three remained prolonged but underwent tonsillectomy with no intervention, and three received hematology consultations. One patient had lupus anticoagulant, one had Hageman Factor deficiency, and one was cleared for surgery with no diagnosis. All patients underwent tonsillectomy with no episodes of postoperative bleeding. CONCLUSIONS: Preoperative PT/PTT provides no additional information than does a bleeding history for the general pediatric population undergoing tonsillectomy. This should only be done in selective cases Where warranted by history.
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Catholic Univ Korea, Coll Med, Dept Lab Med, Seoul 137701, South Korea
Catholic Univ Korea, Coll Med, Lab Dev, Seoul 137701, South Korea
Catholic Univ Korea, Coll Med, Evaluat Ctr, Seoul 137701, South KoreaCatholic Univ Korea, Coll Med, Dept Lab Med, Seoul 137701, South Korea
Kim, Hyunjung
Kim, Yonggoo
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Catholic Univ Korea, Coll Med, Dept Lab Med, Seoul 137701, South Korea
Catholic Univ Korea, Coll Med, Lab Dev, Seoul 137701, South Korea
Catholic Univ Korea, Coll Med, Evaluat Ctr, Seoul 137701, South KoreaCatholic Univ Korea, Coll Med, Dept Lab Med, Seoul 137701, South Korea
机构:
Univ Fed Santa Maria, Grad Program Pharmaceut Sci, Santa Maria, BrazilUniv Fed Santa Maria, Grad Program Pharmaceut Sci, Santa Maria, Brazil
Mastella, Aline K.
de Carvalho, Jose A. M.
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Univ Fed Santa Maria, Grad Program Pharmaceut Sci, Santa Maria, BrazilUniv Fed Santa Maria, Grad Program Pharmaceut Sci, Santa Maria, Brazil
de Carvalho, Jose A. M.
Pereira, Karla N.
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Univ Fed Santa Maria, Grad Program Pharmaceut Sci, Santa Maria, BrazilUniv Fed Santa Maria, Grad Program Pharmaceut Sci, Santa Maria, Brazil
Pereira, Karla N.
das Neves, Yasmin S.
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Univ Fed Santa Maria, Grad Program Pharmaceut Sci, Santa Maria, BrazilUniv Fed Santa Maria, Grad Program Pharmaceut Sci, Santa Maria, Brazil
das Neves, Yasmin S.
Stein, Carolina S.
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Univ Fed Santa Maria, Grad Program Pharmaceut Sci, Santa Maria, BrazilUniv Fed Santa Maria, Grad Program Pharmaceut Sci, Santa Maria, Brazil
Stein, Carolina S.
Bochi, Guilherme V.
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Univ Fed Santa Maria, Ctr Hlth Sci, Grad Program Pharmacol, Santa Maria, RS, BrazilUniv Fed Santa Maria, Grad Program Pharmaceut Sci, Santa Maria, Brazil
Bochi, Guilherme V.
Moresco, Rafael N.
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Univ Fed Santa Maria, Grad Program Pharmaceut Sci, Santa Maria, Brazil
Univ Fed Santa Maria, Ctr Ciencias Saude, Dept Anal Clin & Toxicol, Ave Roraima 1000,Predio 26,Sala 1401, BR-97105900 Santa Maria, RS, BrazilUniv Fed Santa Maria, Grad Program Pharmaceut Sci, Santa Maria, Brazil
机构:
Christian Med Coll & Hosp, Dept Hepatol, Vellore 632004, Tamil Nadu, IndiaChristian Med Coll & Hosp, Dept Hepatol, Vellore 632004, Tamil Nadu, India
Sajith, K.
Goel, Ashish
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Christian Med Coll & Hosp, Dept Hepatol, Vellore 632004, Tamil Nadu, IndiaChristian Med Coll & Hosp, Dept Hepatol, Vellore 632004, Tamil Nadu, India
Goel, Ashish
Ramachandran, Jeyamani
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Christian Med Coll & Hosp, Dept Hepatol, Vellore 632004, Tamil Nadu, IndiaChristian Med Coll & Hosp, Dept Hepatol, Vellore 632004, Tamil Nadu, India
Ramachandran, Jeyamani
Priya, Shenbaga
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Christian Med Coll & Hosp, Dept Transfus Med & Immunohaematol, Vellore 632004, Tamil Nadu, IndiaChristian Med Coll & Hosp, Dept Hepatol, Vellore 632004, Tamil Nadu, India
Priya, Shenbaga
Nair, Sukesh
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Christian Med Coll & Hosp, Dept Transfus Med & Immunohaematol, Vellore 632004, Tamil Nadu, IndiaChristian Med Coll & Hosp, Dept Hepatol, Vellore 632004, Tamil Nadu, India
Nair, Sukesh
Eapen, C.
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Christian Med Coll & Hosp, Dept Hepatol, Vellore 632004, Tamil Nadu, IndiaChristian Med Coll & Hosp, Dept Hepatol, Vellore 632004, Tamil Nadu, India