Glutathione depletion in CYP2E1 expressing liver cells induces toxicity due to the activation of P38 mapk and reduction of NF-αB DNA binding activity

被引:0
|
作者
Wu, DF [1 ]
Cederbaum, AI [1 ]
机构
[1] CUNY Mt Sinai Sch Med, Dept Pharmacol & Biol Chem, New York, NY 10029 USA
关键词
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
650
引用
收藏
页码:325 / 325
页数:1
相关论文
共 50 条
  • [21] The anacardic 6-pentadecyl salicylic acid induces macrophage activation via the phosphorylation of ERK1/2, JNK, P38 kinases and NF-κB
    Gnanaprakasam, J. N. Rashida
    Estrada-Muniz, Elizabet
    Vega, Libia
    [J]. INTERNATIONAL IMMUNOPHARMACOLOGY, 2015, 29 (02) : 808 - 817
  • [22] Sulforaphane down-regulates COX-2 expression by activating p38 and inhibiting NF-κB-DNA-binding activity in human bladder T24 cells
    Shan, Yujuan
    Wu, Kun
    Wang, Wei
    Wang, Shuran
    Lin, Na
    Zhao, Ruifang
    Cassidy, Aedin
    Bao, Yongping
    [J]. INTERNATIONAL JOURNAL OF ONCOLOGY, 2009, 34 (04) : 1129 - 1134
  • [23] Angiotensin II induces NF-κB, JNK and p38 MAPK activation in monocytic cells and increases matrix metalloproteinase-9 expression in a PKC- and Rho kinase-dependent manner
    Yaghooti, H.
    Firoozrai, M.
    Fallah, S.
    Khorramizadeh, M. R.
    [J]. BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH, 2011, 44 (03) : 193 - 199
  • [24] Thrombin induces MCP-1 expression through Rho-kinase and subsequent p38MAPK/NF-κB signaling pathway activation in vascular endothelial cells
    Kawanami, Daiji
    Matoba, Keiichiro
    Kanazawa, Yasushi
    Ishizawa, Sho
    Yokota, Tamotsu
    Utsunomiya, Kazunori
    [J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2011, 411 (04) : 798 - 803
  • [25] Agonistic targeting of TLR1/TLR2 induces p38 MAPK-dependent apoptosis and NFκB-dependent differentiation of AML cells
    Eriksson, Mia
    Pena-Martinez, Pablo
    Ramakrishnan, Ramprasad
    Chapellier, Marion
    Hogberg, Carl
    Glowacki, Gabriella
    Orsmark-Pietras, Christina
    Velasco-Hernandez, Talia
    Lazarevic, Vladimir Lj
    Juliusson, Gunnar
    Cammenga, Jorg
    Mulloy, James C.
    Richter, Johan
    Fioretos, Thoas
    Ebert, Benjamin L.
    Jaras, Marcus
    [J]. BLOOD ADVANCES, 2017, 1 (23) : 2046 - 2057
  • [26] HBP induces the expression of monocyte chemoattractant protein-1 via the FAK/PI3K/AKT and p38 MAPK/NF-κB pathways in vascular endothelial cells
    Chang, Mengling
    Guo, Feng
    Zhou, Zengding
    Huang, Xiaoqin
    Yi, Lei
    Dou, Yi
    Huan, Jingning
    [J]. CELLULAR SIGNALLING, 2018, 43 : 85 - 94
  • [27] IL-1β induces FGF-2 production via PI 3-kinase/p38/NF-κB pathways in corneal endothelial cells
    Lee, Jeong Goo
    Kay, EunDuck P.
    [J]. FASEB JOURNAL, 2011, 25
  • [28] Crosstalk Between the Glucocorticoid Receptor, NF-κB and P38 MAPK in Pulmonary Epithelial Cells Enables Increased Inflammatory Signaling Due to Enhanced Toll-Like Receptor 2 Expression
    Bansal, A.
    Mostafa, M. M.
    Kooi, C.
    Shah, S.
    Leigh, R.
    Gerber, A. N.
    Newton, R.
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2020, 201
  • [29] Visfatin/PBEF/Nampt induces EMMPRIN and MMP-9 production in macrophages via the NAMPT-MAPK (p38, ERK1/2)-NF-κB signaling pathway
    Fan, Yuqi
    Meng, Shu
    Wang, Yue
    Cao, Jiatian
    Wang, Changqian
    [J]. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2011, 27 (04) : 607 - 615
  • [30] Curcumenol isolated from Curcuma zedoaria suppresses Akt-mediated NF-κB activation and p38 MAPK signaling pathway in LPS-stimulated BV-2 microglial cells
    Lo, Jia Ye
    Kamarudin, Muhamad Noor Alfarizal
    Hamdi, Omer Abdalla Ahmed
    Awang, Khalijah
    Kadir, Habsah Abdul
    [J]. FOOD & FUNCTION, 2015, 6 (11) : 3550 - 3559