Epacadostat plus pembrolizumab in patients with advanced melanoma: Phase 1 and 2 efficacy and safety results from ECHO-202/KEYNOTE-037

被引：0
|
作者：
Hamid, O. [1 ]
Gajewski, T. F. [2 ,3 ]
Frankel, A. E. [4 ]
Bauer, T. M. [5 ]
Olszanski, A. J. [6 ]
Luke, J. J. [7 ]
Balmanoukian, A. S. [1 ]
Schmidt, E. V. [8 ]
Sharkey, B. [9 ]
Maleski, J. [9 ]
Jones, M. J. [9 ]
Gangadhar, T. C. [10 ]
机构：
[1] Angeles Clin & Res Inst, Res, Los Angeles, CA USA
[2] Univ Chicago, Dept Pathol, 5841 S Maryland Ave, Chicago, IL 60637 USA
[3] Univ Chicago, Dept Med, Sect Hematol Oncol, 5841 S Maryland Ave, Chicago, IL 60637 USA
[4] Univ Texas Southwestern Med Ctr Dallas, Internal Med, Dallas, TX 75390 USA
[5] Sarah Cannon Res Inst Tennessee Oncol, Drug Dev Unit, Nashville, TN USA
[6] Fox Chase Canc Ctr, Dept Med Hematol Oncol, 7701 Burholme Ave, Philadelphia, PA 19111 USA
[7] Univ Chicago, Hematol Oncol, Chicago, IL 60637 USA
[8] Merck & Co Inc, Oncol Clin Res, Kenilworth, NJ USA
[9] Incyte Corp, Drug Dev, Wilmington, DE USA
[10] Univ Penn, Abramson Canc Ctr, Hematol Oncol Div, Med, Philadelphia, PA 19104 USA
来源：
ANNALS OF ONCOLOGY | 2017年 / 28卷
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
1214O
引用
收藏
页数：2
相关论文
共 50 条
  • [21] Efficacy and safety of pembrolizumab monotherapy in patients with advanced thyroid cancer in the phase 2 KEYNOTE-158 study
    Oh, Do-Youn
    Algazi, Alain
    Capdevila, Jaume
    Longo, Federico
    Miller, Jr Wilson
    Bing, Jerry Tan Chun
    Eduardo Bonilla, Carlos
    Chung, Hyun Cheol
    Guren, Tormod K.
    Lin, Chia-Chi
    Motola-Kuba, Daniel
    Shah, Manisha
    Hadoux, Julien
    Yao, Lili
    Jin, Fan
    Norwood, Kevin
    Lebellec, Loic
    CANCER, 2023, 129 (08) : 1195 - 1204
  • [22] Pembrolizumab plus either epacadostat or placebo for cisplatin-ineligible urothelial carcinoma: results from the ECHO-307/KEYNOTE-672 study
    Necchi, Andrea
    van der Heijden, Michiel S.
    Trukhin, Dmytro
    Peer, Avivit
    Gurney, Howard
    Alekseev, Boris Y.
    Parnis, Francis X.
    Leibowitz, Raya
    De Santis, Maria
    Grivas, Petros
    Clark, Jason
    Munteanu, Mihaela
    Kataria, Ritesh
    Jia, Calvin
    Balar, Arjun V.
    de Wit, Ronald
    BMC CANCER, 2024, 23 (SUPPL 1)
  • [23] KEYNOTE 029: Phase 1/2 randomized study of pembrolizumab (pembro) plus 2 dose regimens of ipilimumab (ipi) for advanced melanoma
    Atkins, M. B.
    Carlino, M. S.
    Hill, A. G.
    McNeil, C. M.
    Ribas, A.
    Atkinson, V.
    Cebon, J. S.
    Jameson, M. B.
    Hwu, W-J.
    Thompson, J. A.
    Anderson, J.
    Moreno, B. Homet
    Ibrahim, N.
    Long, G. V.
    ANNALS OF ONCOLOGY, 2017, 28
  • [24] Efficacy and Safety of Pembrolizumab in Previously Treated Advanced Neuroendocrine Tumors: Results From the Phase II KEYNOTE-158 Study
    Strosberg, Jonathan
    Mizuno, Nobumasa
    Doi, Toshihiko
    Grande, Enrique
    Delord, Jean-Pierre
    Shapira-Frommer, Ronnie
    Bergsland, Emily
    Shah, Manisha
    Fakih, Marwan
    Takahashi, Shunji
    Piha-Paul, Sarina A.
    O'Neil, Bert
    Thomas, Sajeve
    Lolkema, Martijn P.
    Chen, Menghui
    Ibrahim, Nageatte
    Norwood, Kevin
    Hadoux, Julien
    CLINICAL CANCER RESEARCH, 2020, 26 (09) : 2124 - 2130
  • [25] Phase 2 study of the safety and efficacy of pembrolizumab (pembro) in combination with dabrafenib (D) and trametinib (T) for advanced melanoma (KEYNOTE-022).
    Long, Georgina V.
    Hamid, Omid
    Hodi, F. Stephen
    Lawrence, Donald P.
    Atkinson, Victoria
    Starodub, Alexander
    Carlino, Matteo S.
    Fisher, Rosalie Anne
    Miller, Wilson H.
    Maio, Michele
    Butler, Marcus
    Queirolo, Paola
    Ferrucci, Pier Francesco
    Petrella, Teresa M.
    Schachter, Jacob
    Huang, Yingjie
    Diede, Scott J.
    Ebbinghaus, Scot
    Ribas, Antoni
    JOURNAL OF CLINICAL ONCOLOGY, 2016, 34 (15)
  • [26] Efficacy and Safety of Pembrolizumab in Previously Treated Advanced Cervical Cancer: Results From the Phase II KEYNOTE-158 Study
    Chung, Hyun Cheol
    Ros, Willeke
    Delord, Jean-Pierre
    Perets, Ruth
    Italiano, Antoine
    Shapira-Frommer, Ronnie
    Manzuk, Lyudmila
    Piha-Paul, Sarina A.
    Xu, Lei
    Zeigenfuss, Susan
    Pruitt, Scott K.
    Leary, Alexandra
    JOURNAL OF CLINICAL ONCOLOGY, 2019, 37 (17) : 1470 - +
  • [27] Epacadostat plus nivolumab in patients with advanced solid tumors: Preliminary phase I/II results of ECHO-204.
    Perez, Raymond P.
    Riese, Matthew John
    Lewis, Karl D.
    Saleh, Mansoor N.
    Daud, Adil
    Berlin, Jordan
    Lee, James J.
    Mukhopadhyay, Sutapa
    Zhou, Li
    Serbest, Gul
    Hamid, Omid
    JOURNAL OF CLINICAL ONCOLOGY, 2017, 35
  • [28] Efficacy and safety of pembrolizumab for the treatment of advanced biliary cancer: Results from the KEYNOTE-158 and KEYNOTE-028 studies
    Piha-Paul, Sarina A.
    Oh, Do-Youn
    Ueno, Makoto
    Malka, David
    Chung, Hyun Cheol
    Nagrial, Adnan
    Kelley, Robin K.
    Ros, Willeke
    Italiano, Antoine
    Nakagawa, Kazuhiko
    Rugo, Hope S.
    de Braud, Filippo
    Varga, Andrea Iolanda
    Hansen, Aaron
    Wang, Hui
    Krishnan, Suba
    Norwood, Kevin G.
    Doi, Toshihiko
    INTERNATIONAL JOURNAL OF CANCER, 2020, 147 (08) : 2190 - 2198
  • [29] Pembrolizumab for Advanced Mesothelioma: Results from the Phase 2 KEYNOTE-158 Study
    Yap, T. A.
    Nakagawa, K.
    Fujimoto, N.
    Kuribayashi, K.
    Guren, T.
    Calabro, L.
    Frommer, R. S.
    Gao, B.
    Kao, S.
    Matos, I.
    Planchard, D.
    Chatterjee, A.
    Jin, F.
    Norwood, K.
    Kindler, H. L.
    JOURNAL OF THORACIC ONCOLOGY, 2021, 16 (01) : S3 - S4
  • [30] Antitumor activity and safety of pembrolizumab in patients with advanced recurrent ovarian cancer: Interim results from the phase 2 KEYNOTE-100 study
    Matulonis, Ursula A.
    Shapira-Frommer, Ronnie
    Santin, Alessandro
    Lisyanskaya, Alla Sergeevua
    Pignata, Sandro
    Vergote, Ignace
    Raspagliesi, Francesco
    Sonke, Gabe S.
    Birrer, Michael
    Provencher, Diane M.
    Sehouli, Jalid
    Colombo, Nicoletta
    Gonzalez-Martin, Antonio
    Oaknin, Ana
    Ottevanger, P. B.
    Rudaitis, Vilius
    Katchar, Kia
    Wang, Zhen
    Ruman, Jane
    Ledermann, Jonathan A.
    JOURNAL OF CLINICAL ONCOLOGY, 2018, 36 (15)
12345