Review of dry powder inhalers

被引：121
|
作者：
Prime, D [1 ]
Atkins, PJ [1 ]
Slater, A [1 ]
Sumby, B [1 ]
机构：
[1] GLAXO WELLCOME INC,RES & DEV,RES TRIANGLE PK,NC
来源：
ADVANCED DRUG DELIVERY REVIEWS | 1997年 / 26卷 / 01期
关键词：
dry powder inhalers; chlorofluorocarbon propellants; inhalation device; device design; dose delivery;
D O I：
10.1016/S0169-409X(97)00510-3
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The search for alternatives to metered-dose inhalers has accelerated recently in a bid to find effective products that do not use chlorofluorocarbon (CFC) propellants. This paper reviews the factors to be considered in developing dry powder inhalers (DPIs), particularly the formulation, metering design and flow path in the device. The advantages and disadvantages of current DPIs are discussed and possible future approaches outlined. (C) 1997 Elsevier Science B.V.
引用
收藏
页码：51 / 58
页数：8
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