In vitro activity of oritavancin against planktonic and biofilm states of vancomycin-susceptible and vancomycin-resistant enterococci

被引：10
|
作者：
Yan, Qun [1 ,2 ]
Karau, Melissa J. [1 ]
Patel, Robin [1 ,3 ]
机构：
[1] Mayo Clin, Dept Lab Med & Pathol, Div Clin Microbiol, Rochester, MN 55905 USA
[2] Cent S Univ, Dept Clin Lab, Xiangya Hosp, Changsha, Hunan, Peoples R China
[3] Mayo Clin, Dept Med, Div Infect Dis, Rochester, MN 55905 USA
来源：
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2018年 / 91卷 / 04期
关键词：
Oritavancin; Enterococcus faecalis; Enterococcus faecium; VRE; Biofilm; STAPHYLOCOCCUS-AUREUS; VITRO ACTIVITY; DALBAVANCIN; INFECTIONS; TELAVANCIN; RIFAMPICIN; FAECALIS;
D O I：
10.1016/j.diagmicrobio.2018.03.008
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
We tested the in vitro activity of oritavancin against 60 vancomycin-susceptible enterococci (VSE) and 27 vancomycin-resistant enterococci (VRE). The oritavancin MIC ranged from <= 0.002 to 0.5 mu g/mL; the minimum biofilm bactericidal concentration ranged from <= 0.002 to 2 mu g/mL. Oritavancin has promising in vitro activity against VSE and VRE in both planktonic and biofilm states. (C) 2018 Elsevier Inc. All rights reserved.
引用
收藏
页码：348 / 350
页数：3
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