In vitro activity of oritavancin against planktonic and biofilm states of vancomycin-susceptible and vancomycin-resistant enterococci

被引：10

作者：

Yan, Qun ^{[1
,2
]}

Karau, Melissa J. ^{[1
]}

Patel, Robin ^{[1
,3
]}

机构：

[1] Mayo Clin, Dept Lab Med & Pathol, Div Clin Microbiol, Rochester, MN 55905 USA

[2] Cent S Univ, Dept Clin Lab, Xiangya Hosp, Changsha, Hunan, Peoples R China

[3] Mayo Clin, Dept Med, Div Infect Dis, Rochester, MN 55905 USA

来源：

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2018年 / 91卷 / 04期

关键词：

Oritavancin; Enterococcus faecalis; Enterococcus faecium; VRE; Biofilm; STAPHYLOCOCCUS-AUREUS; VITRO ACTIVITY; DALBAVANCIN; INFECTIONS; TELAVANCIN; RIFAMPICIN; FAECALIS;

D O I：

10.1016/j.diagmicrobio.2018.03.008

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

We tested the in vitro activity of oritavancin against 60 vancomycin-susceptible enterococci (VSE) and 27 vancomycin-resistant enterococci (VRE). The oritavancin MIC ranged from <= 0.002 to 0.5 mu g/mL; the minimum biofilm bactericidal concentration ranged from <= 0.002 to 2 mu g/mL. Oritavancin has promising in vitro activity against VSE and VRE in both planktonic and biofilm states. (C) 2018 Elsevier Inc. All rights reserved.

引用

页码：348 / 350

页数：3

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