Structure based drug design: Selective inhibitors of CDC2 and CDK2

被引：0
|
作者：
Brooks, FE [1 ]
Lum, R [1 ]
Mackman, R [1 ]
Joly, A [1 ]
Shiffman, D [1 ]
机构：
[1] CV Therapeut, Palo Alto, CA 94304 USA
来源：
FASEB JOURNAL | 1997年 / 11卷 / 09期
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
2121
引用
收藏
页码：A1220 / A1220
页数：1
相关论文
共 50 条
  • [11] Cell cycle sibling rivalry - Cdc2 vs. Cdk2
    Kaldis, P
    Aleem, E
    CELL CYCLE, 2005, 4 (11) : 1491 - 1494
  • [12] Structure Based Drug Design Studies on CDK2 Amino Pyrazole Inhibitors Using Autodock Tools
    Srinivasu, Nulaka
    Satyanarayana, K. V. V.
    Murthy, N. Gopala Krishna
    2014 CONFERENCE ON IT IN BUSINESS, INDUSTRY AND GOVERNMENT (CSIBIG), 2014,
  • [13] Design of new inhibitors for CDC2 kinase based on a multiple pseudosubstrate structure
    Sasaki, S
    Hashimoto, T
    Obana, N
    Yasuda, H
    Uehara, Y
    Maeda, A
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1998, 8 (09) : 1019 - 1022
  • [14] Activation of cyclin-dependent kinases CDC2 and CDK2 in hepatocellular carcinoma
    Li, KKW
    Ng, IOL
    Fan, ST
    Albrecht, JH
    Yamashita, K
    Poon, RYC
    LIVER, 2002, 22 (03): : 259 - 268
  • [15] A specific inhibitor of cyclin-dependent protein kinases, CDC2 and CDK2
    Park, SG
    Cheon, JY
    Lee, YH
    Park, JS
    Lee, KY
    Lee, CH
    Lee, SK
    MOLECULES AND CELLS, 1996, 6 (06) : 679 - 683
  • [16] Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5
    Meijer, L
    Borgne, A
    Mulner, O
    Chong, JPJ
    Blow, JJ
    Inagaki, N
    Inagaki, M
    Delcros, JG
    Moulinoux, JP
    EUROPEAN JOURNAL OF BIOCHEMISTRY, 1997, 243 (1-2): : 527 - 536
  • [17] Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5
    Meijer, L.
    Borgne, A.
    Mulner, O.
    Chong, J. P. J.
    European Journal of Biochemistry, 243 (1-2):
  • [18] COEXPRESSION OF CDK2/CDC2 AND RETINOBLASTOMA GENE-PRODUCTS IN COLORECTAL-CANCER
    YAMAMOTO, H
    MONDEN, T
    IKEDA, K
    IZAWA, H
    FUKUDA, K
    FUKUNAGA, M
    TOMITA, N
    SHIMANO, T
    SHIOZAKI, H
    MONDEN, M
    BRITISH JOURNAL OF CANCER, 1995, 71 (06) : 1231 - 1236
  • [19] Cdc2: a monopotent or pluripotent CDK?
    Hu, X.
    Moscinski, L. C.
    CELL PROLIFERATION, 2011, 44 (03) : 205 - 211
  • [20] PHOSPHORYLATION AND ACTIVATION OF THE XENOPUS CDC25 PHOSPHATASE IN THE ABSENCE OF CDC2 AND CDK2 KINASE-ACTIVITY
    IZUMI, T
    MALLER, JL
    MOLECULAR BIOLOGY OF THE CELL, 1995, 6 (02) : 215 - 226
12345