Voxel-based morphometry of auditory and speech-related cortex in stutterers

被引:68
|
作者
Beal, Deryk S.
Gracco, Vincent L.
Lafaille, Sophie J.
De Nil, Luc F.
机构
[1] Univ Toronto, Dept Speech Language Pathol, Toronto, ON M5G 1V7, Canada
[2] Univ Hlth Network, Toronto Western Res Inst, Toronto, ON, Canada
[3] McGill Univ, Sch Commun Sci & Disorders, Montreal, PQ, Canada
[4] Haskins Labs Inc, New Haven, CT 06511 USA
关键词
auditory processing; language processing; magnetic resonance imaging; neuroimaging; stuttering; speech production; voxel-based morphometry;
D O I
10.1097/WNR.0b013e3282202c4d
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Stutterers demonstrate unique functional neural activation patterns during speech production, including reduced auditory activation, relative to nonstutterers. The extent to which these functional differences are accompanied by abnormal morphology of the brain in stutterers is unclear. This study examined the neuroanatomical differences in speech-related cortex between stutterers and nonstutterers using voxel-based morphometry. Results revealed significant differences in localized grey matter and white matter densities of left and right hemisphere regions involved in auditory processing and speech production.
引用
收藏
页码:1257 / 1260
页数:4
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