TGF-β1 and IL-10 modulate IL-1β-induced membrane and soluble ICAM-1 in human myoblasts

被引：17
|
作者：
Marino, M [1 ]
Scuderi, F [1 ]
Mannella, F [1 ]
Bartoccioni, E [1 ]
机构：
[1] Univ Sacred Heart, Inst Gen Pathol, I-00168 Rome, Italy
来源：
JOURNAL OF NEUROIMMUNOLOGY | 2003年 / 134卷 / 1-2期
关键词：
interleukin-1 (IL-1); interleukin-10 (IL-10); transforming growth factor-beta (TGF-beta); intercellular adhesion molecule-1 (ICAM-1); human myoblast; muscle;
D O I：
10.1016/S0165-5728(02)00399-5
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
We have previously shown that interleukin (IL)-1beta and other inflammatory cytokines are able to induce the expression of membrane and soluble intercellular adhesion molecule (ICAM)-1 on human myoblasts. In this paper we found that IL-10 and transforming growth factor (TGF)-beta1 are able to prevent IL-1beta-induced membrane and soluble ICAM-I protein expression on human myoblasts, with different time courses. The effect of both cytokines is associated to a reduction in ICAM-1 mRNA. Our findings suggest that IL-10 and TGF-beta1 are able to influence the inflammatory process in muscle tissue at least in part by means of control of membrane and soluble ICAM-1. (C) 2002 Elsevier Science B.V. All rights reserved.
引用
收藏
页码：151 / 157
页数：7
相关论文
共 50 条
  • [11] Intracellular signaling pathways involved in IL-1β-induced ICAM-1 expression in human lung epithelial cells
    Lin, FS
    Yang, CM
    FASEB JOURNAL, 2004, 18 (05): : A946 - A946
  • [12] The influence of diesel exhaust particles on mononuclear phagocytic cell-derived cytokines:: IL-10, TGF-β and IL-1β
    Pacheco, KA
    Tarkowski, M
    Sterritt, C
    Negri, J
    Rosenwasser, LJ
    Borish, L
    CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 2001, 126 (03): : 374 - 383
  • [13] INFLAMMATORY PROFILE OF NEUROTROPHINS, IL-6, IL1-β, TNF-α, VEGF, ICAM-1 AND TGF-β IN THE HUMAN WALDEYER'S RING
    Bianchi, E.
    Magliulo, G.
    Marcotullio, D.
    Taurone, S.
    Ierino, R.
    Pompili, E.
    Fumagalli, L.
    Parnigotto, P. P.
    Di Liddo, R.
    Artico, M.
    EUROPEAN JOURNAL OF INFLAMMATION, 2013, 11 (03): : 763 - 775
  • [14] Upregulation of Interleukin-10 (IL-10) by interleukin-1β (IL-1β) in Human Muller cells
    Habib, Sofia Noor
    Niyadurupola, Nuwan
    Broadway, David Charles
    Sanderson, Julie
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2019, 60 (09)
  • [15] ROLE OF ICAM-1 AND IL-1 IN THE INDUCTION AND ENHANCEMENT OF ENDOTOXIN-INDUCED UVEITIS IN MICE
    TANOUCHI, Y
    KOGISO, M
    MIMURA, Y
    NAGASAWA, H
    HIMENO, K
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 1993, 34 (04) : 1477 - 1477
  • [16] ICAM-1 EXPRESSION IS NOT REGULATED BY IL-1 IN HUMAN-MELANOMA CELL-LINES
    BOCCALETTI, V
    WANG, Z
    TEMPONI, M
    MANGANONI, AM
    FERRONE, S
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1994, 103 (03) : 450 - 450
  • [17] Associations of interleukin (IL)-1β, IL-1 receptor antagonist, and IL-10 with dental caries
    Cogulu, Dilsah
    Onay, Huseyin
    Ozdemir, Yasemin
    Aslan, Gulcin I.
    Ozkinay, Ferda
    Kutukculer, Necil
    Eronat, Cemal
    JOURNAL OF ORAL SCIENCE, 2015, 57 (01) : 31 - 36
  • [18] Lipoxin A4 inhibits IL-1β-induced IL-8 and ICAM-1 expression in 1321N1 human astrocytoma cells
    Decker, Yann
    McBean, Gethin
    Godson, Catherine
    AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2009, 296 (06): : C1420 - C1427
  • [19] Lidocaine and activated endothelial IL-1β, IL-6 and IL-8 concentrations and ICAM-1 Expression
    Lan, W.
    Harmon, D.
    Wang, J. H.
    Shorten, G.
    Redmond, P.
    EUROPEAN JOURNAL OF ANAESTHESIOLOGY, 2004, 21 : 120 - 120
  • [20] Interleukin-1α (IL-1α), IL-1β, IL-1 receptor type I, IL-1 receptor antagonist, and TGF-β1 mRNAs in pediatric astrocytomas, ependymomas, and primitive neuroectodermal tumors
    Ilyin, SE
    Gonzalez-Gomez, I
    Gilles, FH
    Plata-Salaman, CR
    MOLECULAR AND CHEMICAL NEUROPATHOLOGY, 1998, 33 (02) : 125 - 137
12345