Postoperative Analgesic Efficacy of Preemptive and Postoperative Lornoxicam or Tramadol in Lumbar Disc Surgery

被引:2
|
作者
Coskun, Esma [1 ]
Dincer, Emine [2 ]
Turan, Guldem [3 ]
Ozgultekin, Asu [2 ]
机构
[1] Private Mozaik Hosp, Dept Anaesthesiol & Reanimat, Antakya, Turkey
[2] Haydarpasa Numune Training & Res Hosp, Clin Anaesthesiol & Reanimat, Istanbul, Turkey
[3] Fatih Sultan Mehmet Training & Res Hosp, Clin Anaesthesiol & Reanimat, Istanbul, Turkey
关键词
Analgesia; lornoxicam; lumbar disc surgery; tramadol; PAIN-CONTROL; DOUBLE-BLIND; PREOPERATIVE LORNOXICAM; PREVENTIVE ANALGESIA; RANDOMIZED-TRIAL; TONSILLECTOMY; TOLERABILITY; PHARMACOLOGY; MORPHINE; SAFETY;
D O I
10.5152/TJAR.2019.60963
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Objective: To compare preemptive and postoperative analgesic efficacy of tramadol and lornoxicam administered before anaesthesia induction in lumbar discectomy. Methods: This randomised, double-blind trial was conducted on 60 ASA I and II patients undergoing lumbar discectomy. Group L (n=30) received 3x8 mg day(-1) lornoxicam, and Group T (n=30) received 3x1.5 mg kg(-1) day(-1) tramadol. A verbal rating scale (VRS), the duration of effective analgesia, the number of additional analgesics used, adverse effects and patient satisfaction were evaluated at the postoperative 30th minute and 1st, 2nd, 4th, 6th, 8th, 12th and 24th hours. Results: There were no significant differences between Groups L and T regarding demographic and clinical characteristics, the number of additional analgesics and the duration of effective analgesia, adverse effects and patient satisfaction. VRS scores of the patients in Group T were significantly higher than those in Group L at the postoperative 30th minute (p=0.050) and the 1st hour (p=0.005). Conclusion: Lornoxicam, which was used for preemptive and postoperative analgesia in lumbar disc surgery, had provided adequate and effective analgesia such as tramadol. Moreover, preemptive analgesia was quite effective in prevention and treatment of postoperative pain.
引用
收藏
页码:375 / 381
页数:7
相关论文
共 50 条
  • [21] Efficacy of lornoxicam in postoperative analgesia after total knee replacement surgery
    Inan, Nurten
    Ozcan, Namik
    Takmaz, Suna Akin
    Ozcan, Ayfle
    Erdogan, Ipek
    Baltaci, Bulent
    AGRI-THE JOURNAL OF THE TURKISH SOCIETY OF ALGOLOGY, 2007, 19 (02): : 38 - 45
  • [22] Analgesic activity of tramadol and pentazocine in postoperative pain
    Magrini, M
    Rivolta, G
    Bolis, C
    Furiosi, D
    INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY RESEARCH, 1998, 18 (02) : 87 - 92
  • [23] Analgesic efficacy of topical tramadol in the control of postoperative pain in children after tonsillectomy
    Akbay, Buket Kocaman
    Yildizbas, Sahnur
    Guclu, Ender
    Yilmaz, Suleyman
    Iskender, Abdulkadir
    Ozturk, Ozcan
    JOURNAL OF ANESTHESIA, 2010, 24 (05) : 705 - 708
  • [24] Analgesic efficacy of topical tramadol in the control of postoperative pain in children after tonsillectomy
    Buket Kocaman Akbay
    Sahnur Yildizbas
    Ender Guclu
    Suleyman Yilmaz
    Abdulkadir Iskender
    Ozcan Ozturk
    Journal of Anesthesia, 2010, 24 : 705 - 708
  • [25] Early efficacy of postoperative rehabilitation training for lumbar disc herniation
    Yuwei Zhu
    Shuang Xia
    Weihang Yang
    Fengchao Shi
    Hongjian Ji
    BMC Sports Science, Medicine and Rehabilitation, 15
  • [26] Early efficacy of postoperative rehabilitation training for lumbar disc herniation
    Zhu, Yuwei
    Xia, Shuang
    Yang, Weihang
    Shi, Fengchao
    Ji, Hongjian
    BMC SPORTS SCIENCE MEDICINE AND REHABILITATION, 2023, 15 (01)
  • [27] Lornoxicam delivered by PCA is effective and safe for postoperative pain control in lumbar spine surgery
    Zhumadilov, Agzam
    Amirzhanova, Aida
    Zlotnik, Alexandr
    Shapira, Yoram
    BRITISH JOURNAL OF ANAESTHESIA, 2012, 108 : 424 - 425
  • [28] Efficacy and safety of lornoxicam in an early postoperative period
    Nikoda, V. V.
    Mayachkin, R. B.
    Bondarenko, A., V
    TERAPEVTICHESKII ARKHIV, 2007, 79 (08) : 28 - 33
  • [29] Comparison of tramadol, tramadol-metamizol and tramadol-lornoxicam administered by intravenous PCA in management of postoperative pain
    Kemal, Sibel Ozcakir
    Sahin, Saziye
    Apan, Alparslan
    AGRI-THE JOURNAL OF THE TURKISH SOCIETY OF ALGOLOGY, 2007, 19 (04): : 24 - 31
  • [30] Which has the least immunity depression during postoperative analgesia - morphine, tramadol, or tramadol with lornoxicam?
    Wang, Z. Y.
    Wang, C. Q.
    Yang, J. J.
    Sun, J.
    Huang, Y. H.
    Tang, Q. F.
    Qian, Y. N.
    CLINICA CHIMICA ACTA, 2006, 369 (01) : 40 - 45