Postoperative Analgesic Efficacy of Preemptive and Postoperative Lornoxicam or Tramadol in Lumbar Disc Surgery

被引:2
|
作者
Coskun, Esma [1 ]
Dincer, Emine [2 ]
Turan, Guldem [3 ]
Ozgultekin, Asu [2 ]
机构
[1] Private Mozaik Hosp, Dept Anaesthesiol & Reanimat, Antakya, Turkey
[2] Haydarpasa Numune Training & Res Hosp, Clin Anaesthesiol & Reanimat, Istanbul, Turkey
[3] Fatih Sultan Mehmet Training & Res Hosp, Clin Anaesthesiol & Reanimat, Istanbul, Turkey
关键词
Analgesia; lornoxicam; lumbar disc surgery; tramadol; PAIN-CONTROL; DOUBLE-BLIND; PREOPERATIVE LORNOXICAM; PREVENTIVE ANALGESIA; RANDOMIZED-TRIAL; TONSILLECTOMY; TOLERABILITY; PHARMACOLOGY; MORPHINE; SAFETY;
D O I
10.5152/TJAR.2019.60963
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Objective: To compare preemptive and postoperative analgesic efficacy of tramadol and lornoxicam administered before anaesthesia induction in lumbar discectomy. Methods: This randomised, double-blind trial was conducted on 60 ASA I and II patients undergoing lumbar discectomy. Group L (n=30) received 3x8 mg day(-1) lornoxicam, and Group T (n=30) received 3x1.5 mg kg(-1) day(-1) tramadol. A verbal rating scale (VRS), the duration of effective analgesia, the number of additional analgesics used, adverse effects and patient satisfaction were evaluated at the postoperative 30th minute and 1st, 2nd, 4th, 6th, 8th, 12th and 24th hours. Results: There were no significant differences between Groups L and T regarding demographic and clinical characteristics, the number of additional analgesics and the duration of effective analgesia, adverse effects and patient satisfaction. VRS scores of the patients in Group T were significantly higher than those in Group L at the postoperative 30th minute (p=0.050) and the 1st hour (p=0.005). Conclusion: Lornoxicam, which was used for preemptive and postoperative analgesia in lumbar disc surgery, had provided adequate and effective analgesia such as tramadol. Moreover, preemptive analgesia was quite effective in prevention and treatment of postoperative pain.
引用
收藏
页码:375 / 381
页数:7
相关论文
共 50 条
  • [1] Postoperative Analgesic Efficacy of Intravenous Dexketoprofen in Lumbar Disc Surgery
    Yazar, Mehmet Akif
    Inan, Nurten
    Ceyhan, Aysegul
    Sut, Esra
    Dikmen, Bayazit
    JOURNAL OF NEUROSURGICAL ANESTHESIOLOGY, 2011, 23 (03) : 193 - 197
  • [2] Efficacy and tolerability of lornoxicam versus tramadol in postoperative pain
    Staunstrup, H
    Ovesen, J
    Larsen, UT
    Elbaek, K
    Larsen, U
    Kroner, K
    JOURNAL OF CLINICAL PHARMACOLOGY, 1999, 39 (08): : 834 - 841
  • [3] Efficacy of intravenous paracetamol, metamizol and lornoxicam on postoperative pain and morphine consumption after lumbar disc surgery
    Dilmen, Ozlem Korkmaz
    Tunali, Yusuf
    Cakmakkaya, Ozlem S.
    Yentur, Ercument
    Tutuncu, Ayse C.
    Tureci, Ercan
    Bahar, Mois
    EUROPEAN JOURNAL OF ANAESTHESIOLOGY, 2010, 27 (05) : 428 - 432
  • [4] The analgesic efficacy of preoperative versus postoperative lornoxicam in varicocele repair
    Inanoglu, Kerem
    Gorur, Sadik
    Akkurt, Cagla Ozbakis
    Guven, Oguz E.
    Kararmaz, Alper
    JOURNAL OF CLINICAL ANESTHESIA, 2007, 19 (08) : 587 - 590
  • [5] Comparison efficacy and tolerability of preemptively used lornoxicam and tramadol for postoperative pain
    Kirdemir, P.
    Marsan, A.
    Ozkavak, S.
    Ediz, N.
    Gogus, N.
    EUROPEAN JOURNAL OF ANAESTHESIOLOGY, 2004, 21 : 199 - 199
  • [6] ANALGESIC ORAL EFFICACY OF TRAMADOL HYDROCHLORIDE IN POSTOPERATIVE PAIN
    SUNSHINE, A
    OLSON, NZ
    ZIGHELBOIM, I
    DECASTRO, A
    MINN, FL
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 1992, 51 (06) : 740 - 746
  • [7] Comparison of the analgesic effects of paracetamol and tramadol in lumbar disc surgery
    Yilmaz, Mehmet Ziya
    Sarihasan, Bahriye Binnur
    Kelsaka, Ebru
    Tas, Nilay
    Caglar Torun, Aysun
    Koksal, Ersin
    Kuruoglu, Enis
    TURKISH JOURNAL OF MEDICAL SCIENCES, 2015, 45 (02) : 438 - 442
  • [8] The Comparison of Preemptive Oral Tramadol, Gabapentin Tramadol and Parasetamol Tramadol Combination on the Efficacy of Postoperative Pain Control in Breast Reduction Surgery
    Can, Muge
    Hatipoglu, Zehra
    Eser, Cengiz
    Gunes, Yasemin
    CUKUROVA MEDICAL JOURNAL, 2013, 38 (03): : 417 - 425
  • [9] Effect of intravenous dexketoprofen use on postoperative analgesic consumption in patients with lumbar disc surgery
    Kelsaka, Ebru
    Guldogus, Fuat
    Cetinoglu, Erhan
    AGRI-THE JOURNAL OF THE TURKISH SOCIETY OF ALGOLOGY, 2014, 26 (02): : 82 - 86
  • [10] The Effect of Systemic and Regional Use of Magnesium Sulfate on Postoperative Tramadol Consumption in Lumbar Disc Surgery
    Demiroglu, Melek
    Un, Canan
    Ornek, Dilsen Hatice
    Kici, Oya
    Yildirim, Ali Erdem
    Horasanli, Eyup
    Baskan, Semih
    Fikir, Emel
    Gamli, Mehmet
    Dikmen, Bayazit
    BIOMED RESEARCH INTERNATIONAL, 2016, 2016