The human oesophagus is lined by a moist, partially keratinized, stratified squamous epithelium, one important property of which is to serve as a barrier between the outside (luminal) world and the internal world of the organism. This phenomenon in clinical parlance is known as 'oesophageal mucosal resistance'. This article details the structure and functions of the oesophageal mucosa that contribute to its defence against injury upon exposure to refluxed gastric acid.
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Univ Amsterdam, Acad Med Ctr, Div Gastroenterol & Hepatol, NL-1105 AZ Amsterdam, NetherlandsUniv Amsterdam, Acad Med Ctr, Div Gastroenterol & Hepatol, NL-1105 AZ Amsterdam, Netherlands
Hirsch, DP
Tytgat, GNJ
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Univ Amsterdam, Acad Med Ctr, Div Gastroenterol & Hepatol, NL-1105 AZ Amsterdam, NetherlandsUniv Amsterdam, Acad Med Ctr, Div Gastroenterol & Hepatol, NL-1105 AZ Amsterdam, Netherlands
Tytgat, GNJ
Boeckxstaens, GEE
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Univ Amsterdam, Acad Med Ctr, Div Gastroenterol & Hepatol, NL-1105 AZ Amsterdam, NetherlandsUniv Amsterdam, Acad Med Ctr, Div Gastroenterol & Hepatol, NL-1105 AZ Amsterdam, Netherlands
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Univ Durham, Sch Hlth, Wolfson Res Unit, Stockton on Tees TS17 6BH, EnglandUniv Durham, Sch Hlth, Wolfson Res Unit, Stockton on Tees TS17 6BH, England
Mason, J
Hungin, APS
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Univ Durham, Sch Hlth, Wolfson Res Unit, Stockton on Tees TS17 6BH, EnglandUniv Durham, Sch Hlth, Wolfson Res Unit, Stockton on Tees TS17 6BH, England