LRRK2 ACTIVITY MODULATES PANETH CELL FUNCTION IN CROHN'S DISEASE

被引：0
|
作者：
Kern, Justin
Haritunians, Talin
Wang, Xiang
Malique, Atika
Debebe, Anketse
Ballentine, Samuel
Nguyen, Hoang
De Vicente, Javier
Arguello, Annie
Henry, Anastasia
Peter, Inga
Mcgovern, Dermot P. B.
Estrada, Anthony
Stappenbeck, Thaddeus S.
Liu, Ta-Chiang
机构：
来源：
GASTROENTEROLOGY | 2022年 / 162卷 / 07期
关键词：
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
20
引用
收藏
页码：S8 / S8
页数：1
相关论文
共 50 条
  • [31] Lrrk2 function in neurons
    Abeliovich, A.
    McLeod, D.
    Hammond, R.
    Dowman, J.
    Inoue, K.
    MOVEMENT DISORDERS, 2006, 21 : S401 - S401
  • [32] The synaptic function of LRRK2
    Lee, Seongsoo
    Imai, Yuzuru
    Gehrke, Stephan
    Liu, Song
    Lu, Bingwei
    BIOCHEMICAL SOCIETY TRANSACTIONS, 2012, 40 : 1047 - 1051
  • [33] The GTPase function of LRRK2
    Taymans, Jean-Marc
    BIOCHEMICAL SOCIETY TRANSACTIONS, 2012, 40 : 1063 - 1069
  • [34] LRRK2 and Parkinson's Disease: From Lack of Structure to Gain of Function
    Blanca Ramirez, Marian
    Madero-Perez, Jesus
    Rivero-Rios, Pilar
    Martinez-Salvador, Mar
    Lara Ordonez, Antonio J.
    Fernandez, Belen
    Fdez, Elena
    Hilfiker, Sabine
    CURRENT PROTEIN & PEPTIDE SCIENCE, 2017, 18 (07) : 677 - 686
  • [35] The structure of LRRK2 and the conformational changes that are associated with LRRK2 activation and Parkinson's disease pathogenesis
    Weng, Jui-Hung
    Auto, Philip
    Lu, Tsan-Wen
    Taylor, Susan
    FASEB JOURNAL, 2020, 34
  • [36] LRRK2 Kinase Activity Is Dependent on LRRK2 GTP Binding Capacity but Independent of LRRK2 GTP Binding
    Taymans, Jean-Marc
    Vancraenenbroeck, Renee
    Ollikainen, Petri
    Beilina, Alexandra
    Lobbestael, Evy
    De Maeyer, Marc
    Baekelandt, Veerle
    Cookson, Mark R.
    PLOS ONE, 2011, 6 (08):
  • [37] The Structure of LRRK2 and the Conformational Changes that are Associated with LRRK2 Activation and Parkinson's Disease Pathogenesis
    Weng, Jui-Hung
    BIOPHYSICAL JOURNAL, 2020, 118 (03) : 41A - 41A
  • [38] The role of LRRK2 in regulating microglial activity in Parkinson's disease (PD)
    Brooker, S.
    Thomas, A.
    Krainc, D.
    MOVEMENT DISORDERS, 2024, 39 : S417 - S418
  • [39] Functional variants in the LRRK2 gene confer shared effects on risk for Crohn's disease and Parkinson's disease
    Hui, Ken Y.
    Fernandez-Hernandez, Heriberto
    Hu, Jianzhong
    Schaffner, Adam
    Pankratz, Nathan
    Hsu, Nai-Yun
    Chuang, Ling-Shiang
    Carmi, Shai
    Villaverde, Nicole
    Li, Xianting
    Rivas, Manual
    Levine, Adam P.
    Bao, Xiuliang
    Labrias, Philippe R.
    Haritunians, Talin
    Ruane, Darren
    Gettler, Kyle
    Chen, Ernie
    Li, Dalin
    Schiff, Elena R.
    Pontikos, Nikolas
    Barzilai, Nir
    Brant, Steven R.
    Bressman, Susan
    Cheifetz, Adam S.
    Clark, Lorraine N.
    Daly, Mark J.
    Desnick, Robert J.
    Duerr, Richard H.
    Katz, Seymour
    Lencz, Todd
    Myers, Richard H.
    Ostrer, Harry
    Ozelius, Laurie
    Payami, Haydeh
    Peter, Yakov
    Rioux, John D.
    Segal, Anthony W.
    Scott, William K.
    Silverberg, Mark S.
    Vance, Jeffery M.
    Ubarretxena-Belandia, Iban
    Foroud, Tatiana
    Atzmon, Gil
    Pe'er, Itsik
    Ioannou, Yiannis
    McGovern, Dermot P. B.
    Yue, Zhenyu
    Schadt, Eric E.
    Cho, Judy H.
    SCIENCE TRANSLATIONAL MEDICINE, 2018, 10 (423)
  • [40] MACROPHAGE LRRK2 HYPERACTIVITY IMPAIRS AUTOPHAGY AND INDUCES PANETH CELL DYSFUNCTION AND INTESTINAL INFLAMMATION
    Sun, Shengxiang
    Hodel, Miki
    Wang, Xiang
    De Vicente, Javier
    Haritunians, Talin
    Debebe, Anketse
    Ma, Changqing
    Malique, Atika
    Hoang Nguyen
    Agam, Maayan
    Goo, Marisa
    Mishra, Richa
    Kluss, Jillian H.
    Frein, Jennifer
    Foster, Amanda
    Ballentine, Samuel
    Kern, Justin
    Yang, Shaohong
    Mengesha, Emebet
    Balasubramanian, Iyshwarya
    Arguello, Annie
    Estrada, Anthony
    Gao, Nan
    Peter, Inga
    Mcgovern, Dermot P. B.
    Henry, Anastasia
    Stappenbeck, Thaddeus S.
    Liu, Ta-Chiang
    GASTROENTEROLOGY, 2024, 166 (05) : S46 - S46
12345