Surface proteins of Streptococcus agalactiae and horizontal gene transfer

被引:15
|
作者
Bröker, G [1 ]
Spellerberg, B [1 ]
机构
[1] Univ Ulm, Dept Med Microbiol & Hyg, D-89081 Ulm, Germany
关键词
surface protein; recombination; streptococcus; mobile genetic element;
D O I
10.1016/j.ijmm.2004.06.018
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Streptococcus agalactiae is responsible for serious infectious diseases in neonates, immuno-compromised adult patients and causes bovine mastitis in animal hosts. Genome sequencing projects revealed strong indications for horizontal gene transfer events leading to virulence acquisition and genetic diversity in this species. Bacterial surface proteins establish the first contact with host tissues and represent interesting targets for the exchange of virulence properties among different streptococci. This review will focus on horizontal gene transfer events in characterized S. agalactiae surface proteins, mobile genetic elements adjacent to the corresponding genes and will discuss potential mechanisms of transfer. (C) 2004 Elsevier GmbH. All rights reserved.
引用
收藏
页码:169 / 175
页数:7
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